TB-Profiler result

Run: ERR11050024
Summary

Run ID: ERR11050024

Sample name:

Date: 02-04-2023 08:00:23

Number of reads: 3090789

Percentage reads mapped: 99.75

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.17
mshA 576113 p.Arg256Gly missense_variant 0.31
rpoC 764534 p.Arg389Gly missense_variant 0.16
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.29
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.35
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168428 c.2184delG frameshift_variant 1.0
PPE35 2168649 c.1963delG frameshift_variant 1.0
PPE35 2168905 p.Ile570Val missense_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.3
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.25
folC 2746275 p.Val442Phe missense_variant 1.0
Rv2752c 3064823 p.Val457Leu missense_variant 0.16
fbiD 3339734 p.Ala206Gly missense_variant 0.44
fbiD 3339751 p.Ala212Pro missense_variant 0.2
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
rpoA 3878597 c.-90G>C upstream_gene_variant 0.29
rpoA 3878641 c.-134C>G upstream_gene_variant 0.8
embC 4240409 p.Pro183Ala missense_variant 0.17
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.35
embB 4248328 c.1815G>C synonymous_variant 0.19
ethR 4327072 c.-477G>C upstream_gene_variant 1.0
whiB6 4338200 p.Asp108His missense_variant 0.16
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407678 c.525G>C synonymous_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0