TB-Profiler result

Run: ERR11050219
Summary

Run ID: ERR11050219

Sample name:

Date: 02-04-2023 16:43:02

Number of reads: 2953833

Percentage reads mapped: 99.52

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6878 c.-424T>C upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576618 p.His424Pro missense_variant 0.29
ccsA 620029 c.139C>T synonymous_variant 1.0
rpoC 764367 p.Gly333Ala missense_variant 0.35
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.33
mmpL5 778422 c.58delG frameshift_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406101 p.Pro414Ser missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.22
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102656 c.387C>T synonymous_variant 1.0
ndh 2102817 p.Leu76Val missense_variant 0.13
katG 2156417 c.-306T>C upstream_gene_variant 1.0
PPE35 2170035 p.Val193Gly missense_variant 0.19
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2222124 c.1041C>T synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.33
pepQ 2860159 p.Ala87Gly missense_variant 0.31
ald 3087816 p.Cys333Gly missense_variant 0.17
fbiD 3339734 p.Ala206Gly missense_variant 0.25
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568425 c.255T>G synonymous_variant 0.38
whiB7 3568428 c.252A>G synonymous_variant 0.5
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
rpoA 3878597 c.-90G>C upstream_gene_variant 0.48
rpoA 3878608 c.-101C>G upstream_gene_variant 0.38
rpoA 3878613 c.-106A>C upstream_gene_variant 0.6
rpoA 3878641 c.-134C>G upstream_gene_variant 0.43
clpC1 4038318 p.Pro796Leu missense_variant 1.0
embC 4240409 p.Pro183Ala missense_variant 0.41
embC 4240421 p.Glu187* stop_gained 0.33
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.47
embB 4247033 p.Ser174Arg missense_variant 0.27
embB 4248328 c.1815G>C synonymous_variant 0.24
whiB6 4338200 p.Asp108His missense_variant 0.28
whiB6 4338595 c.-75delG upstream_gene_variant 1.0