TB-Profiler result

Run: ERR11050882

Summary

Run ID: ERR11050882

Sample name:

Date: 04-04-2023 01:09:39

Number of reads: 4761377

Percentage reads mapped: 99.62

Strain: lineage4.7

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576116 p.Ala257Pro missense_variant 0.18
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304749 p.Pro607Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471786 n.-60T>G upstream_gene_variant 0.17
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170675 c.-63G>C upstream_gene_variant 1.0
Rv1979c 2222497 p.Leu223Pro missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
whiB7 3568431 c.249C>G synonymous_variant 0.26
whiB7 3568797 c.-118G>T upstream_gene_variant 1.0
fbiB 3642275 c.741A>G synonymous_variant 1.0
rpoA 3878641 c.-134C>G upstream_gene_variant 0.17
clpC1 4040235 p.Gly157Ala missense_variant 0.26
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247024 p.Pro171Ala missense_variant 0.11
embB 4248329 p.Met606Leu missense_variant 0.16
embB 4249732 c.3219C>G synonymous_variant 0.99
ethR 4328030 p.Ala161Gly missense_variant 0.32
ethR 4328039 p.Arg164Pro missense_variant 0.24
whiB6 4338595 c.-75delG upstream_gene_variant 1.0