TB-Profiler result

Run: ERR11067774
Summary

Run ID: ERR11067774

Sample name:

Date: 05-04-2023 09:09:52

Number of reads: 2505603

Percentage reads mapped: 99.46

Strain: lineage4.1.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7323 p.Pro8Ala missense_variant 0.19
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8933 c.1632G>C synonymous_variant 0.17
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.2
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoB 763249 p.Asp1148Gly missense_variant 0.13
rpoC 764263 c.894G>A synonymous_variant 0.77
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 765326 p.His653Asn missense_variant 0.86
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776659 p.Asp608Asn missense_variant 0.18
mmpL5 777320 c.1161C>G synonymous_variant 0.74
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168371 p.Ala748Thr missense_variant 0.8
PPE35 2168501 p.Phe704Leu missense_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449012 p.Pro170Leu missense_variant 0.83
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3611974 c.1143A>C synonymous_variant 0.88
fbiA 3641258 p.Pro239Gln missense_variant 0.2
fbiB 3642365 c.831G>A synonymous_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4247024 p.Pro171Ala missense_variant 0.31
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407634 p.Thr190Ile missense_variant 0.78