TB-Profiler result

Run: ERR11068819
Summary

Run ID: ERR11068819

Sample name:

Date: 07-04-2023 03:02:15

Number of reads: 2955594

Percentage reads mapped: 99.51

Strain: lineage4.1.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9647 c.2346C>G synonymous_variant 0.22
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
mshA 576113 p.Arg256Gly missense_variant 0.33
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 766064 p.Val899Ile missense_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303965 c.1035G>A synonymous_variant 0.2
fbiC 1304014 p.Pro362Ser missense_variant 0.2
fbiC 1304193 c.1263G>A synonymous_variant 0.17
Rv1258c 1406984 c.357A>C synonymous_variant 0.29
Rv1258c 1407012 p.Ala110Val missense_variant 0.4
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1834841 p.Lys434Glu missense_variant 0.12
tlyA 1917970 c.31_33delCTAinsTTG synonymous_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
eis 2715085 p.Ser83Asn missense_variant 0.17
pepQ 2859997 p.Ala141Val missense_variant 0.11
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3641876 c.342C>T synonymous_variant 0.11
clpC1 4038218 c.2487G>A synonymous_variant 0.18
embC 4240432 c.570C>T synonymous_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4244324 c.1092T>C synonymous_variant 0.11
embB 4246619 p.Ile36Val missense_variant 0.18
embB 4248329 p.Met606Leu missense_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408468 c.-266G>T upstream_gene_variant 0.12