Run ID: ERR11465162
Sample name:
Date: 06-01-2024 14:54:36
Number of reads: 7221609
Percentage reads mapped: 99.58
Strain: lineage4.4.1.1;lineage4.1
Drug-resistance: Sensitive
Drug | Resistance | Supporting mutations |
---|---|---|
Rifampicin | ||
Isoniazid | ||
Ethambutol | ||
Pyrazinamide | ||
Streptomycin | ||
Fluoroquinolones | ||
Moxifloxacin | ||
Ofloxacin | ||
Levofloxacin | ||
Ciprofloxacin | ||
Aminoglycosides | ||
Amikacin | ||
Capreomycin | ||
Kanamycin | ||
Cycloserine | ||
Ethionamide | ||
Clofazimine | ||
Para-aminosalicylic_acid | ||
Delamanid | ||
Bedaquiline | ||
Linezolid |
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.1 | Euro-American | T;X;H | None | 0.61 |
lineage4.4 | Euro-American | S;T | None | 0.37 |
lineage4.4.1 | Euro-American (S-type) | S;T | None | 0.37 |
lineage4.4.1.1 | Euro-American | S;Orphans | None | 0.35 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 |
gyrA | 9138 | p.Gln613Glu | missense_variant | 0.35 |
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 |
mshA | 576108 | p.Ala254Gly | missense_variant | 0.22 |
rpoC | 765150 | p.Gly594Glu | missense_variant | 0.68 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
mmpL5 | 777310 | p.Gly391Ser | missense_variant | 0.76 |
mmpL5 | 777416 | c.1065G>T | synonymous_variant | 0.27 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
inhA | 1673363 | c.-839G>A | upstream_gene_variant | 0.37 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
ndh | 2102990 | p.Val18Ala | missense_variant | 0.35 |
PPE35 | 2168479 | p.Thr712Pro | missense_variant | 0.32 |
PPE35 | 2169840 | p.Gly258Asp | missense_variant | 0.48 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
Rv2752c | 3066175 | p.Pro6Arg | missense_variant | 0.37 |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 |
Rv3083 | 3448608 | c.105G>A | synonymous_variant | 0.41 |
fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 |
fprA | 3474774 | c.768G>C | synonymous_variant | 0.65 |
whiB7 | 3568418 | c.250_261delGGACGTCCGCGC | conservative_inframe_deletion | 0.89 |
whiB7 | 3568779 | c.-100T>C | upstream_gene_variant | 0.4 |
Rv3236c | 3612665 | p.Val151Ala | missense_variant | 0.35 |
alr | 3841505 | c.-85C>T | upstream_gene_variant | 0.55 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 0.99 |
embC | 4242803 | p.Val981Leu | missense_variant | 0.7 |
embB | 4249408 | c.2895G>A | synonymous_variant | 0.7 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |