TB-Profiler result

Run: ERR11466401
Summary

Run ID: ERR11466401

Sample name:

Date: 2024-10-03T19:13:15.786273

Number of reads: 3846619

Percentage reads mapped: 99.94

Median coverage: 86.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
mmpL5 777119 p.His454Gln missense_variant 0.16 bedaquiline Uncertain significance
clofazimine Uncertain significance
mmpL5 777122 c.1359C>T synonymous_variant 0.17 bedaquiline
clofazimine
mmpL5 777128 c.1353A>G synonymous_variant 0.16 bedaquiline
clofazimine
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
PPE35 2169902 c.711G>C synonymous_variant 0.11 pyrazinamide
kasA 2518809 p.Lys232Arg missense_variant 0.13 isoniazid