TB-Profiler result

Run: ERR1199053
Summary

Run ID: ERR1199053

Sample name:

Date: 15-08-2022 10:14:58

Number of reads: 9728520

Percentage reads mapped: 81.65

Strain: lineage4.6.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.1 Euro-American (Uganda) T2 RD724 1.0
lineage4.6.1.1 Euro-American T2-Uganda RD724 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7539 p.Thr80Ala missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 762836 c.-534C>G upstream_gene_variant 0.38
mmpL5 775639 p.Ile948Val missense_variant 0.99
mmpL5 777399 p.Thr361Arg missense_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406750 c.591C>A synonymous_variant 0.18
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673420 c.-20C>G upstream_gene_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169866 c.747G>C synonymous_variant 0.12
PPE35 2170246 p.Ser123Ala missense_variant 0.91
Rv1979c 2222359 p.Leu269Pro missense_variant 0.95
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2859381 c.1038C>G synonymous_variant 0.21
thyA 3073806 c.666C>G synonymous_variant 0.16
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3475280 p.Val425Gly missense_variant 0.19
fbiB 3642734 c.1200G>C synonymous_variant 0.13
ddn 3987013 p.Gly57Ala missense_variant 0.16
clpC1 4039363 p.Ala448Pro missense_variant 0.19
embC 4240355 p.Ala165Pro missense_variant 0.21
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242822 p.Val987Gly missense_variant 0.3
aftB 4267409 c.1428C>A synonymous_variant 0.2
ethA 4328329 c.-856C>G upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0