TB-Profiler result

Run: ERR1633849

Summary

Run ID: ERR1633849

Sample name:

Date: 21-10-2023 13:25:34

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.7;lineage3

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 0.15
lineage4 Euro-American LAM;T;S;X;H None 0.87
lineage4.7 Euro-American (mainly T) T1;T5 None 0.85
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 0.2
gyrA 8056 p.Arg252Leu missense_variant 0.12
gyrA 9304 p.Gly668Asp missense_variant 0.2
fgd1 491742 c.960T>C synonymous_variant 0.11
rpoC 762434 c.-936T>G upstream_gene_variant 0.13
rpoC 763031 c.-339T>C upstream_gene_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 0.14
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 0.89
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 0.19
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 0.12
thyA 3074424 c.48G>T synonymous_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 0.1
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249732 c.3219C>G synonymous_variant 0.9
ethA 4328212 c.-740delC upstream_gene_variant 0.21
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 0.12
gid 4407704 p.Ala167Pro missense_variant 0.84