TB-Profiler result

Run: ERR1633927
Summary

Run ID: ERR1633927

Sample name:

Date: 18-08-2022 14:49:29

Number of reads: 1186497

Percentage reads mapped: 99.67

Strain: lineage4.3.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 0.99
lineage4.3.2 Euro-American (LAM) LAM3 None 1.0
lineage4.3.2.1 Euro-American (LAM) LAM3 RD761 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5065 c.-175G>A upstream_gene_variant 0.13
gyrA 7222 c.-80C>T upstream_gene_variant 0.91
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 764995 c.1626C>G synonymous_variant 0.93
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800818 p.Lys4Glu missense_variant 0.18
inhA 1674952 p.Pro251Ala missense_variant 0.21
tlyA 1917972 c.33A>G synonymous_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 1.0
thyA 3074047 p.Ala142Val missense_variant 0.2
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethA 4327467 p.Glu3* stop_gained 0.14
gid 4408156 p.Leu16Arg missense_variant 1.0