TB-Profiler result

Run: ERR1750874
Summary

Run ID: ERR1750874

Sample name:

Date: 31-03-2023 14:57:26

Number of reads: 13633889

Percentage reads mapped: 97.28

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.19
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.22
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.15
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.15
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.17
rrs 1472993 n.1148G>T non_coding_transcript_exon_variant 0.17
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.14
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.14
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.14
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.17
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.16
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.15
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474153 n.496C>A non_coding_transcript_exon_variant 0.12
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.21
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.15
rrl 1474202 n.545T>A non_coding_transcript_exon_variant 0.19
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.21
rrl 1474488 n.831G>C non_coding_transcript_exon_variant 0.12
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.16
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.16
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 0.19
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.17
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.14
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.14
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.19
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.14
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.16
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.19
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.12
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.12
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.2
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.22
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.28
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.22
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.22
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.18
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.18
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.19
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.21
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.2
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.18
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.15
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 0.99
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
Rv3083 3448500 c.-4A>G upstream_gene_variant 1.0
Rv3083 3448501 c.-3G>T upstream_gene_variant 1.0
clpC1 4039729 p.Asp326Asn missense_variant 0.99
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448500 c.-3_*1407del transcript_ablation 1.0