TB-Profiler result

Run: ERR1750899
Summary

Run ID: ERR1750899

Sample name:

Date: 31-03-2023 14:59:14

Number of reads: 7443814

Percentage reads mapped: 96.91

Strain: lineage4.1.1.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 0.99
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781435 c.-125G>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.15
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.18
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.17
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.11
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.24
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.27
rrs 1472571 n.726G>A non_coding_transcript_exon_variant 0.27
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.22
rrs 1472606 n.761C>G non_coding_transcript_exon_variant 0.24
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.18
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.16
rrs 1472645 n.800G>C non_coding_transcript_exon_variant 0.21
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.14
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.15
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.16
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.11
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.11
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.19
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.2
rrl 1474488 n.831G>C non_coding_transcript_exon_variant 0.19
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.26
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.26
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.25
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.25
rrl 1474516 n.859C>G non_coding_transcript_exon_variant 0.21
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.29
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.22
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.26
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 0.26
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.24
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.2
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.21
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.21
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.21
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.2
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.13
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.14
rrl 1475481 n.1824C>A non_coding_transcript_exon_variant 0.17
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.13
rrl 1475536 n.1879C>A non_coding_transcript_exon_variant 0.17
rrl 1475538 n.1881T>A non_coding_transcript_exon_variant 0.17
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.15
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.15
rrl 1475548 n.1891C>T non_coding_transcript_exon_variant 0.18
rrl 1475549 n.1892T>C non_coding_transcript_exon_variant 0.18
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.18
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.18
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.23
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.11
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.14
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.14
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.14
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.13
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.17
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.17
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.19
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.33
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.33
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.19
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.18
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.14
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.11
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.11
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.12
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.99
embA 4242643 c.-590C>T upstream_gene_variant 0.99
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407798 c.405G>T synonymous_variant 1.0