TB-Profiler result

Run: ERR2179696
Summary

Run ID: ERR2179696

Sample name:

Date: 10-08-2022 17:51:14

Number of reads: 5866486

Percentage reads mapped: 99.46

Strain: lineage4.4.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4 Euro-American S;T None 0.99
lineage4.4.2 Euro-American T1;T2 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 0.99
rpsL 781395 c.-165T>C upstream_gene_variant 0.99
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472340 n.495C>A non_coding_transcript_exon_variant 0.13
rrs 1472876 n.1031G>T non_coding_transcript_exon_variant 0.18
rrs 1472882 n.1037A>G non_coding_transcript_exon_variant 0.18
rrs 1472949 n.1104C>A non_coding_transcript_exon_variant 0.17
rrl 1474711 n.1054G>T non_coding_transcript_exon_variant 0.14
rrl 1475272 n.1615G>A non_coding_transcript_exon_variant 0.2
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.11
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.11
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.17
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.18
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.13
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.14
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.14
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.12
rrl 1475982 n.2325G>A non_coding_transcript_exon_variant 0.12
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.12
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.12
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.11
rrl 1476103 n.2446C>T non_coding_transcript_exon_variant 0.12
inhA 1674090 c.-112C>T upstream_gene_variant 0.98
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154047 p.Trp689Arg missense_variant 0.94
katG 2156405 c.-295delC upstream_gene_variant 0.52
Rv1979c 2223293 c.-129A>G upstream_gene_variant 0.99
Rv2752c 3065256 p.Met312Ile missense_variant 0.99
Rv2752c 3066099 p.Met31Ile missense_variant 0.99
ald 3086788 c.-32T>C upstream_gene_variant 0.99
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246508 c.-6G>A upstream_gene_variant 1.0
aftB 4268928 c.-92C>T upstream_gene_variant 1.0
aftB 4269375 c.-539G>A upstream_gene_variant 0.99
whiB6 4338595 c.-75delG upstream_gene_variant 1.0