TB-Profiler result

Run: ERR2229025
Summary

Run ID: ERR2229025

Sample name:

Date: 31-03-2023 16:31:44

Number of reads: 972440

Percentage reads mapped: 99.6

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoB 760770 p.Ile322Val missense_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777247 c.1234C>A synonymous_variant 0.13
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1673357 c.-83G>A upstream_gene_variant 0.16
fabG1 1673359 c.-81T>C upstream_gene_variant 0.16
fabG1 1673361 c.-79C>G upstream_gene_variant 0.12
fabG1 1673380 c.-60C>G upstream_gene_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154465 c.1647T>C synonymous_variant 0.11
PPE35 2167955 c.2658A>C synonymous_variant 0.17
PPE35 2167965 p.Ala883Gly missense_variant 0.11
PPE35 2168244 p.Ser790Thr missense_variant 0.1
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2169287 c.1326T>C synonymous_variant 0.15
PPE35 2169902 c.711G>C synonymous_variant 0.12
PPE35 2170048 p.Leu189Val missense_variant 0.56
PPE35 2170053 p.Thr187Ser missense_variant 0.5
PPE35 2170147 p.Ser156Ala missense_variant 0.15
PPE35 2170235 c.378T>C synonymous_variant 0.11
PPE35 2170238 c.375T>G synonymous_variant 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518879 c.765A>G synonymous_variant 0.24
kasA 2518882 c.768C>A synonymous_variant 0.22
folC 2746524 p.Ala359Ser missense_variant 0.15
folC 2747377 c.222C>A synonymous_variant 0.13
thyX 3068011 c.-66C>T upstream_gene_variant 0.12
thyX 3068015 c.-70T>G upstream_gene_variant 0.12
thyA 3074514 c.-43T>C upstream_gene_variant 0.11
fprA 3474904 p.Gly300Arg missense_variant 0.11
alr 3841546 c.-126C>A upstream_gene_variant 0.24
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244448 c.1220delC frameshift_variant 0.13
embA 4244849 c.1617C>G synonymous_variant 0.2
embB 4246548 p.Pro12Gln missense_variant 0.29
embB 4246555 c.42G>C synonymous_variant 0.31
embB 4246556 p.Ala15Pro missense_variant 0.31
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0