TB-Profiler result

Run: ERR2432996
Summary

Run ID: ERR2432996

Sample name:

Date: 31-03-2023 18:11:40

Number of reads: 549672

Percentage reads mapped: 99.61

Strain: lineage4.1.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7171 c.-131C>T upstream_gene_variant 0.11
gyrA 7323 p.Pro8Ala missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490756 c.-27T>G upstream_gene_variant 0.15
fgd1 491591 p.Lys270Met missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 764317 c.948C>T synonymous_variant 0.11
rpoC 765150 p.Gly594Glu missense_variant 0.96
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776659 p.Asp608Asn missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673576 p.His46Leu missense_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155657 p.Lys152Met missense_variant 0.11
PPE35 2168501 p.Phe704Leu missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.13
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3642413 c.879G>T synonymous_variant 0.1
embC 4241509 c.1647A>C synonymous_variant 0.11
embC 4241512 c.1650_1651insAAC conservative_inframe_insertion 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243769 c.537C>T synonymous_variant 0.12
embA 4245044 c.1812G>A synonymous_variant 0.11
embB 4247121 p.Ser203Leu missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0