TB-Profiler result

Run: ERR2514712
Summary

Run ID: ERR2514712

Sample name:

Date: 20-10-2023 10:45:32

Number of reads: 1983030

Percentage reads mapped: 96.89

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Rifampicin
Isoniazid
Ethambutol
Pyrazinamide
Streptomycin
Fluoroquinolones
Moxifloxacin
Ofloxacin
Levofloxacin
Ciprofloxacin
Aminoglycosides
Amikacin
Capreomycin
Kanamycin
Cycloserine
Ethionamide
Clofazimine
Para-aminosalicylic_acid
Delamanid
Bedaquiline
Linezolid
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
ccsA 619898 p.Thr3Met missense_variant 0.95
rpoB 760715 c.909C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775878 p.Thr868Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416814 c.534G>A synonymous_variant 0.98
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1833961 c.420C>G synonymous_variant 0.13
rpsA 1833970 c.429G>T synonymous_variant 0.12
rpsA 1833979 c.438T>C synonymous_variant 0.13
rpsA 1833991 c.450C>G synonymous_variant 0.12
rpsA 1834000 c.459G>C synonymous_variant 0.12
rpsA 1834009 c.468C>T synonymous_variant 0.11
rpsA 1834012 c.471G>C synonymous_variant 0.11
rpsA 1834015 c.474G>C synonymous_variant 0.11
rpsA 1834021 c.480C>T synonymous_variant 0.11
rpsA 1834030 c.489C>G synonymous_variant 0.11
rpsA 1834033 c.492C>T synonymous_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2167963 p.Gly884Trp missense_variant 0.93
PPE35 2170675 c.-63G>C upstream_gene_variant 0.97
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249732 c.3219C>G synonymous_variant 0.98
ubiA 4270004 c.-171G>A upstream_gene_variant 0.98
whiB6 4338595 c.-75delG upstream_gene_variant 1.0