TB-Profiler result

Run: ERR2652951
Summary

Run ID: ERR2652951

Sample name:

Date: 31-03-2023 22:24:56

Number of reads: 856705

Percentage reads mapped: 99.74

Strain: lineage4.4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4 Euro-American S;T None 1.0
lineage4.4.1 Euro-American (S-type) S;T None 1.0
lineage4.4.1.1 Euro-American S;Orphans None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6052 c.813T>C synonymous_variant 0.1
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 766500 p.Ala1044Val missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305138 p.Phe736Leu missense_variant 0.1
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475736 n.2079G>T non_coding_transcript_exon_variant 0.12
rpsA 1834015 c.474G>A synonymous_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102990 p.Val18Ala missense_variant 1.0
PPE35 2168528 c.2085T>C synonymous_variant 1.0
PPE35 2169840 p.Gly258Asp missense_variant 1.0
PPE35 2169959 c.654C>T synonymous_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289912 c.-672delT upstream_gene_variant 0.11
kasA 2519284 c.1170C>T synonymous_variant 0.12
folC 2746298 p.Glu434Gly missense_variant 0.12
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448608 c.105G>A synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568501 p.Ala60Val missense_variant 0.12
Rv3236c 3612665 p.Val151Ala missense_variant 1.0
fbiB 3642528 p.Glu332Lys missense_variant 0.11
clpC1 4038724 p.Val661Leu missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246728 p.Ile72Asn missense_variant 0.15
embB 4246885 c.372C>T synonymous_variant 0.12
ubiA 4268936 p.Ala300Pro missense_variant 0.1
whiB6 4338595 c.-75delG upstream_gene_variant 1.0