Run ID: ERR2653098
Sample name:
Date: 31-03-2023 22:31:11
Number of reads: 679108
Percentage reads mapped: 99.47
Strain: lineage4.7
Drug-resistance: Pre-XDR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.7 | Euro-American (mainly T) | T1;T5 | None | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
gyrB | 6620 | p.Asp461His | missense_variant | 1.0 | ofloxacin, moxifloxacin, levofloxacin, fluoroquinolones, ciprofloxacin |
rpoB | 761155 | p.Ser450Leu | missense_variant | 0.97 | rifampicin |
katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid |
embB | 4247730 | p.Gly406Ala | missense_variant | 1.0 | ethambutol |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrB | 5338 | c.99C>T | synonymous_variant | 0.13 |
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
ccsA | 619831 | c.-60T>G | upstream_gene_variant | 0.21 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
mmpL5 | 775715 | c.2766G>A | synonymous_variant | 1.0 |
mmpL5 | 778033 | p.Gln150* | stop_gained | 0.11 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
PPE35 | 2170048 | p.Leu189Val | missense_variant | 0.11 |
PPE35 | 2170053 | p.Thr187Ser | missense_variant | 0.11 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
pncA | 2289070 | p.Phe58Val | missense_variant | 1.0 |
ald | 3087854 | c.1035G>A | synonymous_variant | 0.11 |
alr | 3841071 | p.Gly117Asp | missense_variant | 1.0 |
clpC1 | 4040525 | c.180C>T | synonymous_variant | 1.0 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
embA | 4243977 | p.Ala249Thr | missense_variant | 1.0 |
embB | 4249732 | c.3219C>G | synonymous_variant | 1.0 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |
gid | 4407590 | p.Ala205Thr | missense_variant | 1.0 |