TB-Profiler result

Run: ERR2679288
Summary

Run ID: ERR2679288

Sample name:

Date: 31-03-2023 23:01:15

Number of reads: 184785

Percentage reads mapped: 99.52

Strain: lineage4

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6259 c.1020C>T synonymous_variant 1.0
gyrB 6507 p.Ala423Val missense_variant 1.0
gyrB 6620 p.Asp461Tyr missense_variant 0.2
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8115 p.Thr272Ala missense_variant 0.17
gyrA 8285 c.984C>T synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9656 c.2355C>G synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 765187 c.1818C>T synonymous_variant 1.0
rpoC 765359 p.Ala664Ser missense_variant 0.29
rpoC 766012 c.2643C>G synonymous_variant 1.0
rpoC 766053 p.Arg895His missense_variant 0.4
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775973 p.Leu836Phe missense_variant 1.0
mmpL5 776411 c.2070T>C synonymous_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781421 c.-139C>A upstream_gene_variant 0.95
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154578 p.Gly512Arg missense_variant 0.1
katG 2156007 c.105C>T synonymous_variant 1.0
PPE35 2169759 p.Gly285Val missense_variant 0.15
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518291 p.Lys59Asn missense_variant 1.0
Rv2752c 3066090 c.101delT frameshift_variant 0.4
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086868 p.Ala17Pro missense_variant 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embC 4240320 p.Gln153Arg missense_variant 0.2
embC 4241504 p.Val548Met missense_variant 0.75
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4247075 p.Val188Leu missense_variant 1.0
embB 4248386 c.1875delG frameshift_variant 0.18
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408211 c.-9G>A upstream_gene_variant 1.0