TB-Profiler result

Run: ERR2679308
Summary

Run ID: ERR2679308

Sample name:

Date: 31-03-2023 23:01:44

Number of reads: 188773

Percentage reads mapped: 99.24

Strain: lineage4.1.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1.3 Euro-American T;X;H None 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7853 c.552C>T synonymous_variant 0.3
gyrA 9143 c.1842T>C synonymous_variant 0.29
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9557 c.2256G>C synonymous_variant 1.0
mshA 576723 p.Val459Gly missense_variant 0.22
rpoC 765150 p.Gly594Glu missense_variant 0.88
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781421 c.-139C>A upstream_gene_variant 1.0
fbiC 1303519 p.Ser197Gly missense_variant 0.22
fbiC 1304610 c.1680C>T synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472805 n.960C>G non_coding_transcript_exon_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168643 p.Phe657Tyr missense_variant 0.2
PPE35 2170231 p.Gln128Lys missense_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2725935 c.-258G>C upstream_gene_variant 0.29
ribD 2987309 c.471G>T synonymous_variant 0.18
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
ddn 3987068 c.225C>T synonymous_variant 0.4
ddn 3987074 c.231C>G synonymous_variant 0.33
panD 4044115 p.Val56Ala missense_variant 0.2
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 0.92
ethA 4326419 p.Ala352Glu missense_variant 1.0
whiB6 4338242 p.Gln94Glu missense_variant 0.2
whiB6 4338595 c.-75delG upstream_gene_variant 1.0