TB-Profiler result

Run: ERR2693237
Summary

Run ID: ERR2693237

Sample name:

Date: 31-03-2023 23:02:13

Number of reads: 34496

Percentage reads mapped: 1.71

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.98
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6406 c.-896C>T upstream_gene_variant 1.0
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 8285 c.984C>T synonymous_variant 1.0
rpoC 764566 c.1197C>G synonymous_variant 0.67
rpoC 764575 c.1206T>G synonymous_variant 0.8
rpoC 764581 c.1212T>C synonymous_variant 0.8
rpoC 764582 p.Leu405Met missense_variant 0.8
rpoC 764611 c.1242G>C synonymous_variant 0.86
rpoC 764632 c.1263T>C synonymous_variant 0.83
rpoC 764641 c.1272C>T synonymous_variant 0.83
rpoC 764644 c.1275G>C synonymous_variant 0.83
rpoC 764650 c.1281G>T synonymous_variant 0.86
rpoC 764663 p.Val432Thr missense_variant 1.0
rpoC 764668 c.1299C>T synonymous_variant 1.0
rpoC 764672 p.Gln435Glu missense_variant 1.0
rpoC 764695 c.1326T>C synonymous_variant 0.83
rpoC 764701 c.1332C>G synonymous_variant 0.83
rpoC 764705 p.Leu446Lys missense_variant 0.83
rpoC 764716 c.1347G>C synonymous_variant 0.75
mmpL5 775639 p.Ile948Val missense_variant 1.0
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 1.0
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 1.0
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 1.0
rrs 1472812 n.967A>C non_coding_transcript_exon_variant 1.0
rrl 1475707 n.2050T>C non_coding_transcript_exon_variant 1.0
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 1.0
rrl 1475716 n.2059A>T non_coding_transcript_exon_variant 1.0
rrl 1475756 n.2100_2110delAACCCGCAAGG non_coding_transcript_exon_variant 0.67
rrl 1475770 n.2113_2114insC non_coding_transcript_exon_variant 0.5
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.5
rrl 1475776 n.2119G>T non_coding_transcript_exon_variant 0.5
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.5
rrl 1475783 n.2126T>G non_coding_transcript_exon_variant 0.5
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.6
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.6
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.6
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.6
rrl 1476246 n.2589G>A non_coding_transcript_exon_variant 1.0
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476266 n.2609G>A non_coding_transcript_exon_variant 1.0
rrl 1476279 n.2622G>T non_coding_transcript_exon_variant 1.0
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 1.0
rrl 1476281 n.2624T>A non_coding_transcript_exon_variant 1.0
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 1.0
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 1.0
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 1.0
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 1.0
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 1.0
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 1.0
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 1.0
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>G non_coding_transcript_exon_variant 1.0
rrl 1476356 n.2699C>G non_coding_transcript_exon_variant 0.9
rrl 1476357 n.2700T>A non_coding_transcript_exon_variant 0.9
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 1.0
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 1.0
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.88
rrl 1476404 n.2747G>A non_coding_transcript_exon_variant 0.77
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.85
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.17
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.23
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.15
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.82
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.82
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.8
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.8
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.71
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.71
rrl 1476474 n.2817C>T non_coding_transcript_exon_variant 0.67
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 1.0
embC 4242642 p.Arg927His missense_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embB 4246551 p.Asn13Ser missense_variant 1.0
ethA 4326024 p.Pro484Ser missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0