TB-Profiler result

Run: ERR3439277
Summary

Run ID: ERR3439277

Sample name:

Date: 01-04-2023 02:01:00

Number of reads: 53490

Percentage reads mapped: 2.28

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.95
lineage4.9 Euro-American (H37Rv-like) T1 None 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 9143 c.1842T>C synonymous_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
fbiC 1304153 p.Pro408Gln missense_variant 0.67
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 1.0
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 1.0
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 1.0
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 1.0
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 1.0
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.75
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.67
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 1.0
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 1.0
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 1.0
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0
rrl 1475767 n.2110G>T non_coding_transcript_exon_variant 1.0
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 1.0
rrl 1475781 n.2124T>C non_coding_transcript_exon_variant 1.0
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.4
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.4
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.62
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.62
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 1.0
rrl 1475877 n.2220C>T non_coding_transcript_exon_variant 1.0
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 1.0
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 1.0
rrl 1475892 n.2235A>C non_coding_transcript_exon_variant 1.0
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 1.0
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 1.0
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 1.0
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 1.0
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 1.0
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 1.0
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 1.0
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 1.0
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 1.0
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 1.0
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 1.0
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 1.0
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 1.0
rrl 1476322 n.2665C>A non_coding_transcript_exon_variant 0.33
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.46
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.54
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.21
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.26
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.16
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.53
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.89
rrl 1476359 n.2702C>T non_coding_transcript_exon_variant 0.56
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.35
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.95
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.5
rrl 1476381 n.2724G>A non_coding_transcript_exon_variant 0.56
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.89
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.64
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.67
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.16
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.58
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.53
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.46
rrl 1476428 n.2771C>A non_coding_transcript_exon_variant 0.88
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.91
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.33
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.16
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.16
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.17
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.17
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.47
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.59
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.7
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
ndh 2103173 c.-132delG upstream_gene_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155503 c.609C>T synonymous_variant 1.0
Rv2752c 3065472 c.720C>T synonymous_variant 0.67
Rv3083 3448783 p.Val94Ile missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embA 4242970 c.-263C>T upstream_gene_variant 1.0
embA 4243693 p.Gly154Asp missense_variant 0.5
aftB 4267091 c.1746C>A synonymous_variant 0.67
aftB 4267167 p.Gln557Pro missense_variant 0.4
aftB 4269351 c.-515C>T upstream_gene_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0