TB-Profiler result

Run: ERR4024998
Summary

Run ID: ERR4024998

Sample name:

Date: 01-04-2023 04:15:40

Number of reads: 1893185

Percentage reads mapped: 99.61

Strain: lineage4.3.2;lineage4.1.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 0.82
lineage4.1 Euro-American T;X;H None 0.16
lineage4.3.2 Euro-American (LAM) LAM3 None 0.84
lineage4.1.2 Euro-American T;H None 0.18
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491463 c.681G>A synonymous_variant 0.12
fgd1 491591 p.Lys270Met missense_variant 0.18
rpoC 764263 c.894G>A synonymous_variant 0.32
rpoC 764995 c.1626C>G synonymous_variant 0.88
rpoC 765150 p.Gly594Glu missense_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 0.82
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3064966 p.Leu409Pro missense_variant 0.16
thyA 3073868 p.Thr202Ala missense_variant 0.86
thyA 3074657 c.-186C>G upstream_gene_variant 0.78
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4038287 c.2418C>T synonymous_variant 0.88
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 0.25
embB 4248705 p.Pro731Leu missense_variant 0.17
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 0.9