Run ID: ERR4797471
Sample name:
Date: 01-04-2023 07:40:58
Number of reads: 2894923
Percentage reads mapped: 99.81
Strain: lineage4.9
Drug-resistance: Pre-XDR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.9 | Euro-American (H37Rv-like) | T1 | None | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
gyrA | 7582 | p.Asp94Gly | missense_variant | 1.0 | ofloxacin, moxifloxacin, levofloxacin, fluoroquinolones, ciprofloxacin |
rpoB | 761155 | p.Ser450Leu | missense_variant | 1.0 | rifampicin |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7153 | c.-149G>C | upstream_gene_variant | 1.0 |
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
mshA | 576108 | p.Ala254Gly | missense_variant | 0.27 |
rpoB | 762715 | p.Val970Gly | missense_variant | 0.12 |
rpoB | 762724 | p.Gly973Asp | missense_variant | 0.33 |
rpoC | 764723 | p.Phe452Leu | missense_variant | 0.33 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrs | 1472433 | n.588G>A | non_coding_transcript_exon_variant | 0.11 |
rrs | 1473277 | n.1432G>A | non_coding_transcript_exon_variant | 1.0 |
rrl | 1473890 | n.233T>A | non_coding_transcript_exon_variant | 0.18 |
rrl | 1474624 | n.969delT | non_coding_transcript_exon_variant | 0.14 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
PPE35 | 2170065 | p.Ala183Gly | missense_variant | 0.16 |
fbiD | 3339734 | p.Ala206Gly | missense_variant | 0.14 |
fbiB | 3641478 | c.-57C>T | upstream_gene_variant | 1.0 |
rpoA | 3878641 | c.-134C>G | upstream_gene_variant | 0.19 |
embB | 4246548 | p.Pro12Gln | missense_variant | 0.13 |
embB | 4246555 | c.42G>C | synonymous_variant | 0.13 |
embB | 4246556 | p.Ala15Pro | missense_variant | 0.17 |
embB | 4246563 | p.Leu17Trp | missense_variant | 0.12 |
embB | 4246567 | c.54G>T | synonymous_variant | 0.14 |
embB | 4246584 | p.Arg24Pro | missense_variant | 0.17 |
aftB | 4268619 | p.Val73Gly | missense_variant | 0.34 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |