TB-Profiler result

Run: ERR4816331
Summary

Run ID: ERR4816331

Sample name:

Date: 01-04-2023 14:22:15

Number of reads: 1097051

Percentage reads mapped: 98.73

Strain: lineage4.1.1

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8018 c.717C>A synonymous_variant 0.15
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303146 c.216G>A synonymous_variant 0.15
fbiC 1304177 p.Ala416Gly missense_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473698 n.41G>T non_coding_transcript_exon_variant 0.22
rrl 1474501 n.844A>C non_coding_transcript_exon_variant 0.25
inhA 1674327 p.Asp42Glu missense_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155617 c.495T>C synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2715553 c.-221C>G upstream_gene_variant 0.11
folC 2746461 p.Ser380Gly missense_variant 0.11
folC 2746858 c.741C>T synonymous_variant 0.11
thyA 3074220 c.252A>T synonymous_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612182 p.Ala312Asp missense_variant 0.17
fbiA 3641447 p.Thr302Met missense_variant 1.0
rpoA 3877553 p.Glu319Lys missense_variant 1.0
embC 4240897 c.1035C>G synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4245563 c.-951G>A upstream_gene_variant 0.12
embB 4247378 p.Leu289Val missense_variant 0.14
embB 4249408 c.2895G>A synonymous_variant 1.0
ethR 4327303 c.-246G>A upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0