TB-Profiler result

Run: ERR4816424
Summary

Run ID: ERR4816424

Sample name:

Date: 01-04-2023 14:25:14

Number of reads: 749023

Percentage reads mapped: 99.82

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7533 p.Ala78Ser missense_variant 0.11
gyrA 8536 p.Glu412Gly missense_variant 0.11
fgd1 491027 p.Asn82Thr missense_variant 0.16
mshA 576751 p.Lys468Asn missense_variant 0.2
ccsA 620748 c.858T>G synonymous_variant 0.24
rpoB 761152 p.Leu449Gln missense_variant 0.2
fbiC 1303016 p.Val29Gly missense_variant 0.21
fbiC 1304723 p.Glu598Val missense_variant 0.11
fbiC 1304840 p.Glu637Val missense_variant 0.5
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473257 n.1412G>A non_coding_transcript_exon_variant 0.15
rrl 1474273 n.616A>G non_coding_transcript_exon_variant 0.5
inhA 1674779 p.Pro193His missense_variant 0.11
PPE35 2167916 c.2696delT frameshift_variant 0.12
PPE35 2168400 p.Glu738Ala missense_variant 0.11
PPE35 2170048 p.Leu189Val missense_variant 0.2
pncA 2289776 c.-535C>T upstream_gene_variant 0.13
ahpC 2726265 p.Lys25Gln missense_variant 0.2
ahpC 2726338 p.Val49Gly missense_variant 0.22
folC 2746660 c.938delT frameshift_variant 0.25
Rv3083 3448310 c.-194G>T upstream_gene_variant 0.12
clpC1 4040403 p.Asn101Ser missense_variant 0.13
panD 4044365 c.-84C>A upstream_gene_variant 0.12
embB 4248768 p.Asp752Val missense_variant 0.12