TB-Profiler result

Run: ERR4819649

Summary

Run ID: ERR4819649

Sample name:

Date: 01-04-2023 16:13:51

Number of reads: 1494570

Percentage reads mapped: 99.91

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576751 p.Lys468Asn missense_variant 0.22
rpoB 761152 p.Leu449Gln missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474425 n.768A>G non_coding_transcript_exon_variant 0.33
rrl 1474428 n.771C>T non_coding_transcript_exon_variant 0.33
rrl 1475421 n.1764C>A non_coding_transcript_exon_variant 0.25
rrl 1475724 n.2067C>A non_coding_transcript_exon_variant 0.18