TB-Profiler result

Run: ERR4819947
Summary

Run ID: ERR4819947

Sample name:

Date: 01-04-2023 16:23:45

Number of reads: 711782

Percentage reads mapped: 99.07

Strain: lineage4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 0.95
ccsA 620748 c.858T>G synonymous_variant 0.29
rpoC 764257 c.888G>C synonymous_variant 0.15
rpoC 764266 c.897T>C synonymous_variant 0.15
rpoC 764269 c.900G>C synonymous_variant 0.15
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 766070 c.2701C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777119 p.His454Gln missense_variant 0.19
mmpL5 777122 c.1359C>T synonymous_variant 0.19
mmpL5 777128 c.1353A>G synonymous_variant 0.18
mmpL5 778185 p.Arg99Pro missense_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303016 p.Val29Gly missense_variant 0.33
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155031 p.Ala361Thr missense_variant 0.14
katG 2155594 p.Leu173Gln missense_variant 0.11
PPE35 2167745 p.Thr956Arg missense_variant 0.17
PPE35 2170048 p.Leu189Val missense_variant 0.19
PPE35 2170053 p.Thr187Ser missense_variant 0.19
PPE35 2170189 p.Glu142Gln missense_variant 0.17
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519140 c.1026G>C synonymous_variant 0.1
kasA 2519143 c.1029G>C synonymous_variant 0.11
kasA 2519153 p.Ile347Val missense_variant 0.12
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474767 p.Gly254Ala missense_variant 1.0
Rv3236c 3613099 c.18G>A synonymous_variant 0.12
fbiA 3641447 p.Thr302Met missense_variant 1.0
rpoA 3877553 p.Glu319Lys missense_variant 1.0
clpC1 4039508 c.1197G>C synonymous_variant 0.13
embC 4240897 c.1035C>G synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407822 p.Gln127His missense_variant 0.11