TB-Profiler result

Run: ERR4820159
Summary

Run ID: ERR4820159

Sample name:

Date: 01-04-2023 16:31:22

Number of reads: 3397766

Percentage reads mapped: 99.61

Strain: lineage4.6.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.1 Euro-American (Uganda) T2 RD724 1.0
lineage4.6.1.1 Euro-American T2-Uganda RD724 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7539 p.Thr80Ala missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.1
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.11
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.1
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.11
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.12
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.12
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.15
rrl 1475813 n.2156A>G non_coding_transcript_exon_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170790 c.-178G>T upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878627 c.-120T>G upstream_gene_variant 0.18
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethA 4328329 c.-856C>G upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0