TB-Profiler result

Run: ERR4821364
Summary

Run ID: ERR4821364

Sample name:

Date: 01-04-2023 17:12:43

Number of reads: 1324333

Percentage reads mapped: 99.42

Strain: lineage4.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.1 Euro-American (TUR) H3;H4 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6352 c.-950C>G upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9338 p.Gln679His missense_variant 1.0
rpoB 760664 c.858G>A synonymous_variant 0.13
mmpL5 775631 p.Gln950His missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 779282 p.Asn98Ser missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918530 c.591G>A synonymous_variant 1.0
katG 2154444 c.1668A>C synonymous_variant 1.0
PPE35 2169879 p.Phe245Cys missense_variant 1.0
PPE35 2170048 p.Leu189Val missense_variant 0.12
PPE35 2170748 c.-136C>T upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embC 4242161 p.Ala767Ser missense_variant 0.1
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243388 c.156C>T synonymous_variant 1.0
embB 4248955 c.2442C>T synonymous_variant 1.0
ubiA 4269397 p.Ala146Glu missense_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408245 c.-43A>G upstream_gene_variant 0.11