TB-Profiler result

Run: ERR4828350
Summary

Run ID: ERR4828350

Sample name:

Date: 01-04-2023 18:49:37

Number of reads: 2031722

Percentage reads mapped: 99.5

Strain: lineage4.4.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4 Euro-American S;T None 1.0
lineage4.4.2 Euro-American T1;T2 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6872 c.-430T>C upstream_gene_variant 0.12
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.38
rpoB 760277 c.471G>A synonymous_variant 0.17
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776003 c.2478C>T synonymous_variant 0.11
mmpL5 776008 p.His825Asp missense_variant 0.11
mmpR5 778100 c.-890C>T upstream_gene_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 0.95
fbiC 1303517 p.Met196Lys missense_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1673697 c.-505G>A upstream_gene_variant 0.12
inhA 1674525 c.324C>T synonymous_variant 0.11
rpsA 1833712 c.171C>T synonymous_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2103176 c.-134G>A upstream_gene_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3065912 p.Leu94Phe missense_variant 0.12
Rv2752c 3066099 p.Met31Ile missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448707 c.204G>T synonymous_variant 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474457 p.Val151Ile missense_variant 0.12
ddn 3987269 c.426C>T synonymous_variant 1.0
clpC1 4040850 c.-146G>T upstream_gene_variant 0.14
clpC1 4040853 c.-149T>C upstream_gene_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246508 c.-6G>A upstream_gene_variant 1.0
embB 4247028 p.Leu172Arg missense_variant 0.25
aftB 4268928 c.-92C>T upstream_gene_variant 1.0
aftB 4269375 c.-539G>A upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0