TB-Profiler result

Run: ERR4828443
Summary

Run ID: ERR4828443

Sample name:

Date: 01-04-2023 18:53:15

Number of reads: 983030

Percentage reads mapped: 99.51

Strain: lineage4.4.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4 Euro-American S;T None 1.0
lineage4.4.2 Euro-American T1;T2 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781403 c.-157G>T upstream_gene_variant 0.29
fbiC 1302917 c.-14G>A upstream_gene_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1673394 c.-808A>G upstream_gene_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101837 c.1206G>A synonymous_variant 0.13
katG 2154484 p.Leu543Pro missense_variant 0.29
PPE35 2168757 p.Gln619Arg missense_variant 1.0
PPE35 2169029 p.Asp528Glu missense_variant 0.4
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv1979c 2223331 c.-167C>T upstream_gene_variant 0.22
pncA 2289590 c.-349G>A upstream_gene_variant 0.22
folC 2747099 p.Pro167Leu missense_variant 1.0
Rv2752c 3064659 c.1533G>C synonymous_variant 0.11
Rv2752c 3064776 c.1416T>C synonymous_variant 0.17
Rv2752c 3066099 p.Met31Ile missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448348 c.-156G>A upstream_gene_variant 1.0
Rv3083 3449757 p.Tyr418* stop_gained 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3641458 p.Val306Met missense_variant 1.0
ddn 3986764 c.-79delT upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246508 c.-6G>A upstream_gene_variant 1.0
embB 4247249 p.Gly246Arg missense_variant 1.0
aftB 4268928 c.-92C>T upstream_gene_variant 1.0
aftB 4269375 c.-539G>A upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0