TB-Profiler result

Run: ERR553032
Summary

Run ID: ERR553032

Sample name:

Date: 02-08-2023 08:56:32

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.3.4.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.4 Euro-American (LAM) LAM RD174 1.0
lineage4.3.4.2 Euro-American (LAM) LAM1;LAM4;LAM11 RD174 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490751 c.-32T>G upstream_gene_variant 0.25
rpoB 759620 c.-187A>C upstream_gene_variant 0.18
rpoB 759658 c.-149T>A upstream_gene_variant 0.11
rpoB 761704 p.Gly633Ala missense_variant 0.1
rpoB 761707 p.Asp634Gly missense_variant 1.0
rpoC 764995 c.1626C>G synonymous_variant 1.0
rpoC 766245 p.Gln959Pro missense_variant 0.1
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpS5 779661 c.-756C>T upstream_gene_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303960 c.1030C>A synonymous_variant 0.12
Rv1258c 1406424 p.Ala306Glu missense_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102651 p.Phe131Ser missense_variant 0.13
ndh 2103225 c.-183A>C upstream_gene_variant 0.21
PPE35 2170767 c.-155G>A upstream_gene_variant 0.1
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518151 p.Ser13Arg missense_variant 0.29
Rv2752c 3064912 p.Val427Ala missense_variant 0.11
Rv2752c 3065293 p.Val300Ala missense_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474080 p.Ala25Val missense_variant 0.15
fprA 3474510 c.504C>A synonymous_variant 0.12
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
fbiB 3641919 p.Ala129Thr missense_variant 0.15
alr 3840551 c.870G>C synonymous_variant 0.11
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4039075 p.Arg544Ser missense_variant 0.12
panD 4044191 p.Asp31Asn missense_variant 0.11
embC 4239763 c.-100C>T upstream_gene_variant 1.0
embC 4240776 p.Glu305Gly missense_variant 0.14
embC 4241621 c.1762delC frameshift_variant 0.18
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4248811 c.2298G>T synonymous_variant 0.12
aftB 4269753 c.-917G>A upstream_gene_variant 0.15
ethA 4327827 c.-354A>G upstream_gene_variant 0.18
whiB6 4338317 p.Ser69Pro missense_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0