Run ID: ERR6362673
Sample name:
Date: 02-04-2023 02:41:47
Number of reads: 2060811
Percentage reads mapped: 99.55
Strain: lineage4.3.3
Drug-resistance: HR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.3 | Euro-American (LAM) | mainly-LAM | None | 1.0 |
lineage4.3.3 | Euro-American (LAM) | LAM;T | RD115 | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
fabG1 | 1673432 | c.-8T>A | upstream_gene_variant | 1.0 | isoniazid |
pncA | 2288727 | p.Leu172Pro | missense_variant | 1.0 | pyrazinamide |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 |
gyrA | 8040 | p.Gly247Ser | missense_variant | 1.0 |
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 |
mshA | 576316 | c.969A>G | synonymous_variant | 1.0 |
rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
embR | 1416706 | c.642C>T | synonymous_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrs | 1472632 | n.787C>A | non_coding_transcript_exon_variant | 0.18 |
rrs | 1472790 | n.945T>G | non_coding_transcript_exon_variant | 0.12 |
rrs | 1473265 | n.1420C>A | non_coding_transcript_exon_variant | 0.25 |
rrs | 1473297 | n.1452G>T | non_coding_transcript_exon_variant | 0.29 |
rrl | 1473525 | n.-132delA | upstream_gene_variant | 0.14 |
rrl | 1473734 | n.77C>A | non_coding_transcript_exon_variant | 0.33 |
rrl | 1474444 | n.787G>T | non_coding_transcript_exon_variant | 0.18 |
rrl | 1474478 | n.821C>A | non_coding_transcript_exon_variant | 0.22 |
rrl | 1474517 | n.860C>A | non_coding_transcript_exon_variant | 0.25 |
rrl | 1474689 | n.1032T>C | non_coding_transcript_exon_variant | 0.25 |
rrl | 1474988 | n.1331C>A | non_coding_transcript_exon_variant | 0.22 |
rrl | 1475049 | n.1392C>A | non_coding_transcript_exon_variant | 0.4 |
rrl | 1475295 | n.1638C>A | non_coding_transcript_exon_variant | 0.29 |
rrl | 1475342 | n.1685C>A | non_coding_transcript_exon_variant | 0.18 |
rrl | 1475652 | n.1995C>A | non_coding_transcript_exon_variant | 0.5 |
rrl | 1475662 | n.2005C>A | non_coding_transcript_exon_variant | 0.5 |
rrl | 1475869 | n.2212C>A | non_coding_transcript_exon_variant | 0.18 |
rrl | 1475882 | n.2225C>A | non_coding_transcript_exon_variant | 0.2 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
PPE35 | 2168466 | p.Leu716Arg | missense_variant | 0.1 |
Rv1979c | 2222222 | p.Ile315Val | missense_variant | 0.1 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
kasA | 2518919 | p.Gly269Ser | missense_variant | 0.98 |
ahpC | 2726388 | p.Ala66Ser | missense_variant | 0.15 |
thyA | 3073868 | p.Thr202Ala | missense_variant | 1.0 |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 |
fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 |
clpC1 | 4038287 | c.2418C>T | synonymous_variant | 1.0 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
embB | 4249079 | p.Ser856Arg | missense_variant | 1.0 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |
gid | 4408156 | p.Leu16Arg | missense_variant | 1.0 |