TB-Profiler result

Run: ERR8975151
Summary

Run ID: ERR8975151

Sample name:

Date: 02-04-2023 08:42:13

Number of reads: 2568064

Percentage reads mapped: 99.26

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7571 c.270G>A synonymous_variant 0.1
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 0.99
ccsA 619701 c.-190G>A upstream_gene_variant 0.5
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
Rv1979c 2221949 p.Ala406Thr missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746503 c.1096C>T synonymous_variant 0.14
folC 2747317 c.282C>A synonymous_variant 0.13
folC 2747682 c.-84C>T upstream_gene_variant 0.22
Rv2752c 3067089 c.-898A>G upstream_gene_variant 0.17
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3641667 p.Val45Ile missense_variant 0.2
fbiB 3641748 p.Arg72* stop_gained 0.14
fbiB 3641807 c.273C>G synonymous_variant 1.0
embC 4240352 p.Val164Ile missense_variant 0.12
embC 4241045 p.Gly395Ser missense_variant 0.22
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4247215 c.702C>T synonymous_variant 0.2
embB 4249408 c.2895G>A synonymous_variant 1.0
ethR 4327691 p.Asp48Gly missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0