TB-Profiler result

Run: ERR8975455
Summary

Run ID: ERR8975455

Sample name:

Date: 02-04-2023 08:49:09

Number of reads: 2121474

Percentage reads mapped: 62.56

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.17
rrs 1472953 n.1108_1109insA non_coding_transcript_exon_variant 0.58
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.58
rrs 1472958 n.1114delT non_coding_transcript_exon_variant 0.58
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.46
rrs 1472973 n.1128A>C non_coding_transcript_exon_variant 0.58
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.44
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.57
rrs 1472983 n.1138A>C non_coding_transcript_exon_variant 0.59
rrs 1472986 n.1142delG non_coding_transcript_exon_variant 0.58
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.58
rrs 1472992 n.1147_1148insT non_coding_transcript_exon_variant 0.57
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.56
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.56
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.57
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.56
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.53
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.27
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.25
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.19
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
alr 3840764 c.657G>C synonymous_variant 1.0
embC 4242497 p.Arg879Gly missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245963 p.Val911Ile missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0