TB-Profiler result

Run: ERR9117675
Summary

Run ID: ERR9117675

Sample name:

Date: 02-04-2023 09:28:15

Number of reads: 1742395

Percentage reads mapped: 92.87

Strain: lineage4.8

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.7 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6247 c.1008G>A synonymous_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.5
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.57
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.57
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.67
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.57
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.5
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.5
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.57
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.57
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.57
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.57
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.57
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.7
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.7
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.64
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.73
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.78
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.78
rrs 1472668 n.825_829delGGGTT non_coding_transcript_exon_variant 0.6
rrs 1472675 n.830_831insAGAC non_coding_transcript_exon_variant 0.5
rrs 1472680 n.835C>T non_coding_transcript_exon_variant 0.3
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.75
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.5
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.73
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.73
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.7
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.67
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.22
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.43
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.43
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.33
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.33
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.29
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.33
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.33
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.33
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 0.29
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 0.29
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.29
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.33
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.33
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.33
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.33
rrl 1475760 n.2103C>A non_coding_transcript_exon_variant 0.33
rrl 1475762 n.2105G>C non_coding_transcript_exon_variant 0.33
rrl 1475767 n.2110G>T non_coding_transcript_exon_variant 0.33
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.33
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.15
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.19
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.21
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.18
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.18
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.18
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.18
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.18
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.18
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.18
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.18
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.18
rrl 1476214 n.2557G>C non_coding_transcript_exon_variant 0.18
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.18
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.18
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.19
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.19
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.31
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.38
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.31
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.38
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.38
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.22
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.22
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.22
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.22
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.22
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.22
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.22
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.22
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.33
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.38
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.6
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.56
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.53
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.52
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.5
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.5
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.55
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.6
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.57
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.42
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethR 4327974 p.Met142Ile missense_variant 1.0
ethR 4327975 p.Gln143Lys missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0