TB-Profiler result

Run: ERR9117695
Summary

Run ID: ERR9117695

Sample name:

Date: 02-04-2023 09:28:43

Number of reads: 1408542

Percentage reads mapped: 88.17

Strain: lineage4.1.2.1

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.31 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 0.98
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.33
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.25
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.33
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.45
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.45
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.55
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.58
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.58
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.58
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.65
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.65
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.5
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.35
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.69
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.72
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.72
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.65
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.38
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.33
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.33
rrs 1472683 n.838T>G non_coding_transcript_exon_variant 0.2
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.21
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.13
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.27
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.27
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.21
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.25
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.14
rrl 1473663 n.6A>C non_coding_transcript_exon_variant 1.0
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.67
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.67
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.67
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.67
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.67
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.33
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.43
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.67
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.6
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.6
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.75
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.6
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.8
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.75
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.6
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.75
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 1.0
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.75
rrl 1474584 n.927C>T non_coding_transcript_exon_variant 0.5
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.6
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.67
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.6
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.6
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.4
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.6
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.57
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.29
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.43
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.5
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.4
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.29
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.71
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.4
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.4
rrl 1475783 n.2126T>G non_coding_transcript_exon_variant 0.55
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.5
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.5
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.44
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.44
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.36
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.4
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.5
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.55
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.55
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.5
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.44
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.5
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.5
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.4
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.5
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.5
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 0.38
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.25
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.22
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.25
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.18
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.27
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.38
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.23
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.15
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.38
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.38
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.21
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.14
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.14
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.21
rrl 1476214 n.2557G>C non_coding_transcript_exon_variant 0.27
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.27
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.41
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.41
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.41
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.42
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.47
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.42
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.53
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.44
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.38
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.44
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.44
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.44
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.4
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.38
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.35
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.47
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.47
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.38
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.65
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.65
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.74
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.76
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.79
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.79
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.74
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.74
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.74
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.79
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.8
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.17
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.58
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.38
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.31
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.27
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.33
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.33
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.25
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.18
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168892 p.Thr574Lys missense_variant 0.98
PPE35 2170048 p.Leu189Val missense_variant 0.11
PPE35 2170053 p.Thr187Ser missense_variant 0.11
Rv1979c 2222142 c.1023A>C synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878522 c.-15G>T upstream_gene_variant 0.4
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
whiB6 4338566 c.-45A>G upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0