TB-Profiler result

Run: ERR9117799
Summary

Run ID: ERR9117799

Sample name:

Date: 02-04-2023 09:31:39

Number of reads: 2143681

Percentage reads mapped: 95.23

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575436 p.Pro30Leu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.42
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.67
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.54
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.57
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.21
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.21
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.33
rrs 1472568 n.723C>T non_coding_transcript_exon_variant 0.13
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.5
rrs 1472573 n.728C>A non_coding_transcript_exon_variant 0.14
rrs 1472574 n.729T>C non_coding_transcript_exon_variant 0.13
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.36
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.29
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.57
rrs 1472583 n.738T>C non_coding_transcript_exon_variant 0.13
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.21
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.57
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.57
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.21
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.15
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.31
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.43
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.43
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.38
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.2
rrs 1472958 n.1114delT non_coding_transcript_exon_variant 0.29
rrs 1472969 n.1125_1126delCG non_coding_transcript_exon_variant 0.22
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.22
rrs 1472975 n.1130T>A non_coding_transcript_exon_variant 0.22
rrs 1472977 n.1132G>T non_coding_transcript_exon_variant 0.2
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.2
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.22
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.22
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.18
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.18
rrs 1473026 n.1181T>C non_coding_transcript_exon_variant 0.23
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.23
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.17
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.17
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.16
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.1
rrl 1473566 n.-92G>C upstream_gene_variant 0.13
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474869 n.1212G>A non_coding_transcript_exon_variant 0.5
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.12
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.12
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.22
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.25
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.25
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.4
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.44
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.44
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.44
rrl 1475963 n.2306G>T non_coding_transcript_exon_variant 0.38
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.43
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.43
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.38
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 0.38
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.33
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 0.33
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.33
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.33
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.38
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.25
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.12
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.12
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.1
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.1
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.1
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.1
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.27
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.3
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.24
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.32
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.32
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.32
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.15
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.32
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.38
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.39
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.17
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.32
rpsA 1833772 p.Asn77Lys missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
clpC1 4039729 p.Asp326Asn missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0