TB-Profiler result

Run: ERR9124899
Summary

Run ID: ERR9124899

Sample name:

Date: 02-04-2023 10:50:57

Number of reads: 1312086

Percentage reads mapped: 99.41

Strain: lineage4.4.2;lineage4.4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4 Euro-American S;T None 1.0
lineage4.4.1 Euro-American (S-type) S;T None 0.31
lineage4.4.2 Euro-American T1;T2 None 0.72
lineage4.4.1.1 Euro-American S;Orphans None 0.3
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 759615 c.-192A>C upstream_gene_variant 0.18
rpoB 759620 c.-187A>C upstream_gene_variant 0.27
rpoB 762669 p.Asp955Asn missense_variant 0.35
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
atpE 1460907 c.-138T>C upstream_gene_variant 0.85
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102990 p.Val18Ala missense_variant 0.26
PPE35 2169840 p.Gly258Asp missense_variant 0.2
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726341 p.Val50Gly missense_variant 0.14
Rv2752c 3066099 p.Met31Ile missense_variant 0.74
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448348 c.-156G>A upstream_gene_variant 0.67
Rv3083 3448608 c.105G>A synonymous_variant 0.35
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612665 p.Val151Ala missense_variant 0.29
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246508 c.-6G>A upstream_gene_variant 0.66
aftB 4267643 p.Asp398Glu missense_variant 0.33
aftB 4268928 c.-92C>T upstream_gene_variant 0.56
aftB 4269375 c.-539G>A upstream_gene_variant 0.64
whiB6 4338595 c.-75delG upstream_gene_variant 1.0