TB-Profiler result

Run: ERR9893151
Summary

Run ID: ERR9893151

Sample name:

Date: 02-04-2023 13:27:30

Number of reads: 1956398

Percentage reads mapped: 99.26

Strain: lineage4.2.2.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
lineage4.2.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8688 p.Ala463Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 0.97
mshA 575805 p.Ser153Leu missense_variant 0.13
mshA 576077 c.730C>T synonymous_variant 1.0
ccsA 619831 c.-60T>G upstream_gene_variant 0.31
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406973 p.Ala123Asp missense_variant 0.12
Rv1258c 1407064 p.Ala93Ser missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 0.99
tlyA 1917953 p.Ala5Asp missense_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169767 c.846A>G synonymous_variant 1.0
Rv1979c 2222408 p.Pro253Ala missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518341 p.Asp76Ala missense_variant 1.0
kasA 2519193 p.Leu360Pro missense_variant 0.12
folC 2746317 p.Asp428Asn missense_variant 0.14
folC 2746653 p.Gly316Arg missense_variant 0.13
Rv2752c 3066280 c.-89C>T upstream_gene_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embC 4242351 p.Pro830Leu missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267827 p.Arg337Leu missense_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0