TB-Profiler result

Run: SRR1013592
Summary

Run ID: SRR1013592

Sample name:

Date: 02-04-2023 15:57:56

Number of reads: 5420956

Percentage reads mapped: 99.38

Strain: lineage2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 0.95
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 0.95
mshA 575936 p.Pro197Ser missense_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 0.94
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 0.95
mmpL5 779259 c.-779G>T upstream_gene_variant 0.94
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303165 p.Ser79Arg missense_variant 0.95
Rv1258c 1406952 p.Glu130Gly missense_variant 1.0
embR 1417119 c.221_228dupCCTACGTG frameshift_variant 0.91
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1834177 c.636A>C synonymous_variant 0.93
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 0.93
katG 2156409 c.-298G>T upstream_gene_variant 0.91
PPE35 2167926 p.Leu896Ser missense_variant 0.93
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 0.94
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878586 c.-79A>G upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267647 p.Asp397Gly missense_variant 0.9
ethA 4326666 p.Arg270Cys missense_variant 0.93
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 0.97
gid 4408034 p.Glu57Gln missense_variant 0.94
gid 4408190 p.Glu5Lys missense_variant 0.95