TB-Profiler result

Run: SRR12006044
Summary

Run ID: SRR12006044

Sample name:

Date: 03-04-2023 05:44:26

Number of reads: 7629889

Percentage reads mapped: 89.01

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
gyrA 7581 p.Asp94Asn missense_variant 1.0 ofloxacin, moxifloxacin, levofloxacin, fluoroquinolones, ciprofloxacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 759803 c.-4C>T upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1476336 n.2679C>G non_coding_transcript_exon_variant 0.12
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.22
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.23
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.26
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.28
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.28
rrl 1476423 n.2766T>C non_coding_transcript_exon_variant 0.29
rrl 1476428 n.2771C>A non_coding_transcript_exon_variant 0.27
rrl 1476458 n.2801T>G non_coding_transcript_exon_variant 0.16
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.14
PPE35 2170598 c.15G>A synonymous_variant 1.0