TB-Profiler result

Run: SRR13837447
Summary

Run ID: SRR13837447

Sample name:

Date: 03-04-2023 09:10:37

Number of reads: 881500

Percentage reads mapped: 98.01

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
ccsA 620144 c.255dupT frameshift_variant 1.0
rpoB 760191 p.Val129Phe missense_variant 1.0
rpoB 760311 p.Val169Leu missense_variant 1.0
rpoB 762805 p.Gly1000Asp missense_variant 1.0
rpoB 762963 p.Gly1053Arg missense_variant 1.0
rpoC 763662 p.Ala98Asp missense_variant 1.0
mmpL5 776041 p.Ala814Thr missense_variant 1.0
mmpL5 776070 c.2410delA frameshift_variant 1.0
mmpL5 777800 c.681C>T synonymous_variant 1.0
fbiC 1304996 p.Leu689Ser missense_variant 1.0
Rv1258c 1407148 p.Ala65Ser missense_variant 1.0
embR 1416842 p.Asp169Gly missense_variant 1.0
inhA 1674940 c.739_740insG frameshift_variant 1.0
ndh 2102694 p.Val117Ile missense_variant 1.0
katG 2155865 p.Val83Met missense_variant 1.0
PPE35 2168123 c.2489dupG frameshift_variant 1.0
PPE35 2170268 c.345C>A synonymous_variant 1.0
kasA 2518311 p.Asp66Gly missense_variant 1.0
eis 2714666 p.Tyr223Asp missense_variant 1.0
ahpC 2726589 p.Arg133Ser missense_variant 1.0
Rv2752c 3066289 c.-98T>G upstream_gene_variant 1.0
thyA 3074418 p.Lys18Asn missense_variant 1.0
ald 3087163 c.344_345insC frameshift_variant 1.0
Rv3236c 3612049 c.1068G>C synonymous_variant 1.0
Rv3236c 3612400 c.717G>A synonymous_variant 1.0
fbiB 3642445 p.Ala304Gly missense_variant 1.0
clpC1 4038941 c.1764G>C synonymous_variant 1.0
clpC1 4040104 p.Met201Leu missense_variant 1.0
embC 4241480 c.1618T>C synonymous_variant 1.0
embB 4249483 c.2970C>G synonymous_variant 1.0
aftB 4268164 c.672_673insA frameshift_variant 1.0
ethA 4327641 c.-168G>A upstream_gene_variant 1.0