TB-Profiler result

Run: SRR13861315

Summary

Run ID: SRR13861315

Sample name:

Date: 03-04-2023 09:28:45

Number of reads: 904020

Percentage reads mapped: 30.16

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6406 p.Asn389Lys missense_variant 1.0
mshA 575880 p.His178Pro missense_variant 1.0
mshA 576356 p.Ala337Ser missense_variant 1.0
rpoB 761165 c.1359G>C synonymous_variant 0.12
fbiC 1303517 p.Met196Arg missense_variant 1.0
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.13
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.13
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.13
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.13
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.13
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.12
rrs 1472971 n.1126G>C non_coding_transcript_exon_variant 0.12
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.13
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.12
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.12
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.13
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.13
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.13
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.13
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.13
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.13
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.15
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.13
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 0.14
rrl 1473558 n.-100T>G upstream_gene_variant 1.0
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.48
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.53
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.54
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.55
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.57
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.6
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.6
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.6
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.59
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.59
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.59
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.58
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.56
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.58
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.58
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.58
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.53
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.53
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.54
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.53
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.18
fabG1 1673792 p.Arg118Leu missense_variant 1.0
rpsA 1833709 c.168C>T synonymous_variant 1.0
rpsA 1834448 p.Lys303* stop_gained 1.0
tlyA 1918103 p.Val55Ala missense_variant 1.0
tlyA 1918250 p.Gly104Ala missense_variant 1.0
katG 2156538 c.-427A>T upstream_gene_variant 1.0
Rv1979c 2222544 c.621G>A synonymous_variant 1.0
eis 2715078 c.255C>G synonymous_variant 1.0
folC 2747750 c.-152G>C upstream_gene_variant 1.0
ald 3086982 p.Ala55Pro missense_variant 1.0
Rv3083 3449935 p.Ile478Val missense_variant 1.0
fbiB 3642147 p.Val205Phe missense_variant 1.0
fbiB 3642189 p.Gly219Trp missense_variant 1.0
clpC1 4039120 p.Ser529Ala missense_variant 1.0
clpC1 4039306 p.Gln467Lys missense_variant 0.97
clpC1 4039400 c.1304delA frameshift_variant 1.0
ethA 4327034 p.Tyr147Phe missense_variant 1.0
gid 4408038 p.Ile55Met missense_variant 1.0