TB-Profiler result

Run: SRR13861434
Summary

Run ID: SRR13861434

Sample name:

Date: 03-04-2023 09:31:44

Number of reads: 445267

Percentage reads mapped: 44.57

Strain: lineage4.9

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761135 p.Leu443Phe missense_variant 0.2 rifampicin
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.19 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6242 p.Arg335Lys missense_variant 0.18
gyrB 6250 c.1011A>G synonymous_variant 0.18
gyrB 6253 c.1014G>C synonymous_variant 0.18
gyrA 6634 c.-668T>C upstream_gene_variant 0.18
gyrA 6637 c.-665T>G upstream_gene_variant 0.18
gyrA 6640 c.-662A>G upstream_gene_variant 0.19
gyrA 6649 c.-653T>C upstream_gene_variant 0.22
gyrA 6652 c.-650C>G upstream_gene_variant 0.21
gyrA 6655 c.-647T>C upstream_gene_variant 0.19
gyrA 6670 c.-632G>C upstream_gene_variant 0.25
gyrA 6673 c.-629A>C upstream_gene_variant 0.25
gyrA 6700 c.-602T>C upstream_gene_variant 0.26
gyrA 6703 c.-599G>C upstream_gene_variant 0.26
gyrA 6706 c.-596G>A upstream_gene_variant 0.26
gyrA 6709 c.-593A>G upstream_gene_variant 0.26
gyrA 6712 c.-590G>C upstream_gene_variant 0.26
gyrA 6727 c.-575G>T upstream_gene_variant 0.31
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.31
gyrA 6745 c.-557T>G upstream_gene_variant 0.25
gyrA 6760 c.-542G>C upstream_gene_variant 0.27
gyrA 6778 c.-524C>T upstream_gene_variant 0.23
gyrA 6793 c.-509T>C upstream_gene_variant 0.21
gyrB 6797 p.Gly520Thr missense_variant 0.17
gyrA 6824 c.-478C>T upstream_gene_variant 0.14
gyrA 6841 c.-461T>C upstream_gene_variant 0.14
gyrA 6844 c.-458T>G upstream_gene_variant 0.13
gyrA 6856 c.-446T>C upstream_gene_variant 0.13
gyrA 6862 c.-440C>G upstream_gene_variant 0.13
gyrA 7664 c.363T>C synonymous_variant 0.13
gyrA 7694 c.393A>G synonymous_variant 0.17
gyrA 7710 c.409T>C synonymous_variant 0.19
gyrA 7715 c.414G>C synonymous_variant 0.19
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.16
gyrA 7799 c.498A>G synonymous_variant 0.14
gyrA 7835 c.534A>G synonymous_variant 0.14
gyrA 7838 c.537C>G synonymous_variant 0.15
gyrA 8294 c.993T>C synonymous_variant 0.15
gyrA 8324 c.1023T>C synonymous_variant 0.22
gyrA 8339 c.1038A>G synonymous_variant 0.22
gyrA 8342 c.1041G>C synonymous_variant 0.2
gyrA 8366 c.1065G>C synonymous_variant 0.22
gyrA 8375 c.1074G>C synonymous_variant 0.22
gyrA 8391 p.Tyr364His missense_variant 0.19
gyrA 8399 c.1098T>C synonymous_variant 0.2
gyrA 8420 c.1119T>C synonymous_variant 0.19
gyrA 8423 c.1122G>C synonymous_variant 0.2
gyrA 8442 c.1141C>T synonymous_variant 0.13
gyrA 8453 c.1152A>C synonymous_variant 0.18
gyrA 8462 c.1161A>G synonymous_variant 0.18
gyrA 8471 c.1170T>C synonymous_variant 0.16
gyrA 8480 c.1179C>T synonymous_variant 0.16
gyrA 8486 c.1185T>C synonymous_variant 0.16
gyrA 8489 c.1188A>G synonymous_variant 0.17
gyrA 8498 c.1197C>T synonymous_variant 0.19
gyrA 8504 c.1203G>C synonymous_variant 0.2
gyrA 8516 c.1215T>C synonymous_variant 0.18
gyrA 8519 c.1218A>C synonymous_variant 0.18
gyrA 8537 c.1236G>A synonymous_variant 0.17
gyrA 8546 c.1245T>C synonymous_variant 0.19
gyrA 8552 c.1251C>G synonymous_variant 0.14
gyrA 8556 p.Ala419His missense_variant 0.14
gyrA 8561 c.1260A>C synonymous_variant 0.21
gyrA 8562 c.1261C>T synonymous_variant 0.14
gyrA 8867 c.1566A>G synonymous_variant 0.14
gyrA 8870 c.1569G>C synonymous_variant 0.14
gyrA 8873 c.1572A>C synonymous_variant 0.14
gyrA 8897 c.1596T>C synonymous_variant 0.17
gyrA 8903 c.1602T>C synonymous_variant 0.17
gyrA 8915 c.1614A>G synonymous_variant 0.17
gyrA 8939 c.1638T>C synonymous_variant 0.15
gyrA 8942 c.1641G>C synonymous_variant 0.14
gyrA 8987 c.1686C>G synonymous_variant 0.14
gyrA 8990 c.1689C>G synonymous_variant 0.15
fgd1 491091 c.309T>C synonymous_variant 0.13
fgd1 491106 c.324T>C synonymous_variant 0.23
fgd1 491121 c.339A>G synonymous_variant 0.23
fgd1 491137 p.Glu119Gln missense_variant 0.23
fgd1 491144 p.Ala121Glu missense_variant 0.23
fgd1 491166 c.384G>C synonymous_variant 0.25
fgd1 491181 c.399T>C synonymous_variant 0.18
fgd1 491191 p.Gly137Arg missense_variant 0.18
fgd1 491194 c.412_414delCTAinsTTG synonymous_variant 0.2
fgd1 491202 c.420G>C synonymous_variant 0.17
fgd1 491203 p.Gln141Glu missense_variant 0.18
fgd1 491212 p.Ser144Arg missense_variant 0.18
fgd1 491217 c.435T>C synonymous_variant 0.15
fgd1 491232 c.450T>C synonymous_variant 0.14
fgd1 491244 c.462T>C synonymous_variant 0.18
fgd1 491295 c.513C>G synonymous_variant 0.13
fgd1 491301 c.519C>T synonymous_variant 0.12
fgd1 491508 c.726A>G synonymous_variant 0.15
fgd1 491509 c.727T>C synonymous_variant 0.15
fgd1 491512 p.Asn244Glu missense_variant 0.14
fgd1 491526 c.744T>C synonymous_variant 0.14
fgd1 491547 c.765A>C synonymous_variant 0.14
fgd1 491550 c.768T>C synonymous_variant 0.15
rpoB 761015 c.1209G>C synonymous_variant 0.14
rpoB 761094 c.1288C>T synonymous_variant 0.13
rpoB 761097 p.Ser431Cys missense_variant 0.13
rpoB 761102 c.1296A>G synonymous_variant 0.19
rpoB 761150 c.1344A>C synonymous_variant 0.13
rpoB 761165 c.1359G>C synonymous_variant 0.13
rpoB 761180 c.1374A>C synonymous_variant 0.14
rpoB 761222 c.1416G>C synonymous_variant 0.25
rpoB 761249 c.1443A>G synonymous_variant 0.15
rpoB 761255 c.1449T>G synonymous_variant 0.17
rpoB 761261 c.1455G>T synonymous_variant 0.15
rpoB 761873 c.2067A>G synonymous_variant 0.14
rpoB 761891 c.2085G>C synonymous_variant 0.13
rpoB 761909 c.2103T>C synonymous_variant 0.13
rpoB 761912 c.2106T>C synonymous_variant 0.14
rpoB 761915 p.Asp703Glu missense_variant 0.15
rpoB 761916 p.Asp704Asn missense_variant 0.15
rpoB 761954 c.2148C>G synonymous_variant 0.16
rpoC 762698 c.-672C>T upstream_gene_variant 1.0
rpoB 762958 p.Leu1051Pro missense_variant 0.9
rpoC 763202 c.-168A>C upstream_gene_variant 0.17
rpoC 763835 p.Ala156Met missense_variant 0.13
rpoC 764040 p.Ser224Asn missense_variant 0.19
rpoC 764044 c.675T>C synonymous_variant 0.2
rpoC 764059 c.690G>C synonymous_variant 0.2
rpoC 764381 p.Ser338Thr missense_variant 0.12
rpoC 764858 c.1489T>C synonymous_variant 0.25
rpoC 764872 c.1503A>G synonymous_variant 0.2
rpoC 764911 c.1542A>G synonymous_variant 0.18
rpoC 764923 c.1554A>G synonymous_variant 0.17
rpoC 764932 c.1563C>A synonymous_variant 0.16
rpoC 764968 c.1599T>C synonymous_variant 0.17
rpoC 765007 c.1638T>G synonymous_variant 0.21
rpoC 765019 c.1650A>G synonymous_variant 0.18
rpoC 765022 c.1653G>C synonymous_variant 0.18
rpoC 765034 c.1665T>C synonymous_variant 0.16
rpoC 765508 c.2139C>G synonymous_variant 0.18
rpoC 765553 c.2184C>T synonymous_variant 0.19
rpoC 765556 c.2187G>C synonymous_variant 0.2
rpoC 765559 c.2190G>C synonymous_variant 0.19
rpoC 765578 c.2209C>T synonymous_variant 0.22
rpoC 765583 c.2214G>T synonymous_variant 0.16
rpoC 765631 p.Asp754Glu missense_variant 0.14
rpoC 765734 c.2365T>C synonymous_variant 0.14
rpoC 765739 c.2370G>C synonymous_variant 0.14
rpoC 765751 c.2382C>G synonymous_variant 0.14
rpoC 765753 p.Asp795Ala missense_variant 0.14
rpoC 766630 c.3261G>C synonymous_variant 0.18
rpoC 766645 c.3276A>G synonymous_variant 0.22
rpoC 766651 c.3282T>C synonymous_variant 0.2
rpoC 766657 c.3288A>G synonymous_variant 0.2
rpoC 766672 c.3303T>C synonymous_variant 0.2
rpoC 766738 c.3369G>T synonymous_variant 0.15
rpoC 766750 c.3381C>G synonymous_variant 0.23
rpoC 766765 c.3396A>C synonymous_variant 0.15
rpoC 766801 c.3432C>A synonymous_variant 0.15
rpoC 766804 c.3435A>G synonymous_variant 0.15
rpoC 766861 c.3492G>C synonymous_variant 0.18
rpoC 766864 c.3495G>C synonymous_variant 0.17
rpsL 781892 c.333A>G synonymous_variant 0.15
rpsL 781898 c.339A>T synonymous_variant 0.15
rpsL 781916 c.357T>C synonymous_variant 0.14
rplC 801249 c.441T>G synonymous_variant 0.22
rplC 801255 c.447C>T synonymous_variant 0.3
rplC 801267 c.459A>C synonymous_variant 0.25
rplC 801270 c.462T>C synonymous_variant 0.25
rplC 801276 c.468G>C synonymous_variant 0.25
rplC 801279 c.471G>C synonymous_variant 0.25
rplC 801282 c.474G>C synonymous_variant 0.25
rplC 801301 c.493C>A synonymous_variant 0.21
rplC 801312 c.504G>C synonymous_variant 0.23
rplC 801324 c.516T>C synonymous_variant 0.23
rplC 801336 c.528C>G synonymous_variant 0.23
rplC 801339 c.531T>C synonymous_variant 0.15
rplC 801341 p.Leu178Gln missense_variant 0.15
rplC 801357 c.549T>C synonymous_variant 0.13
rplC 801367 p.Ala187Thr missense_variant 0.13
fbiC 1302962 p.Ala11Gly missense_variant 1.0
fbiC 1303706 p.Leu259Arg missense_variant 1.0
fbiC 1304811 c.1881C>G synonymous_variant 0.14
fbiC 1304817 c.1887T>C synonymous_variant 0.13
fbiC 1304853 c.1923C>G synonymous_variant 0.16
fbiC 1304856 c.1926C>G synonymous_variant 0.15
fbiC 1305384 c.2454G>T synonymous_variant 0.88
fbiC 1305411 c.2481C>T synonymous_variant 0.14
fbiC 1305420 c.2490C>G synonymous_variant 0.14
fbiC 1305423 c.2493T>C synonymous_variant 0.14
fbiC 1305430 p.Val834Thr missense_variant 0.13
fbiC 1305453 c.2523C>G synonymous_variant 0.12
Rv1258c 1406724 p.Gln206Leu missense_variant 1.0
embR 1416800 p.Ala183Gly missense_variant 1.0
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.2
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.2
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.21
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.21
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.23
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.18
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.2
rrl 1473945 n.288T>C non_coding_transcript_exon_variant 0.21
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.17
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.15
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.21
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.14
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.14
rrl 1474056 n.399T>C non_coding_transcript_exon_variant 0.14
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.21
rrl 1474104 n.447G>A non_coding_transcript_exon_variant 0.21
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.21
rrl 1474112 n.455T>A non_coding_transcript_exon_variant 0.21
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.27
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.3
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.33
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.29
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.3
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.3
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.44
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.44
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.33
rrl 1474409 n.756_766delACCCACACGCG non_coding_transcript_exon_variant 0.2
rrl 1474427 n.770A>C non_coding_transcript_exon_variant 0.17
rrl 1474434 n.777T>G non_coding_transcript_exon_variant 0.23
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 0.2
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.19
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.19
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.19
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.19
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.13
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.14
rrl 1474959 n.1302C>T non_coding_transcript_exon_variant 0.14
rrl 1474962 n.1306delG non_coding_transcript_exon_variant 0.15
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.15
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.17
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.15
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 0.15
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.21
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.12
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.13
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.12
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.27
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.41
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.41
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.41
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.41
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.42
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.41
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.41
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.41
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.41
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.43
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.43
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.42
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.38
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.38
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.38
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.41
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.41
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.35
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.33
fabG1 1673153 c.-287C>G upstream_gene_variant 1.0
inhA 1674654 c.453G>C synonymous_variant 0.13
inhA 1674718 c.517A>C synonymous_variant 0.12
inhA 1674771 c.570C>G synonymous_variant 0.14
inhA 1674816 c.615T>C synonymous_variant 0.15
inhA 1674818 p.Ala206Val missense_variant 0.15
inhA 1674828 p.Glu209Asp missense_variant 0.15
inhA 1674829 p.Glu210Gln missense_variant 0.15
inhA 1674834 c.633C>G synonymous_variant 0.15
inhA 1674836 p.Gly212Ala missense_variant 0.15
inhA 1674839 p.Ala213Glu missense_variant 0.15
inhA 1674848 p.Gln216Arg missense_variant 0.17
inhA 1674855 c.654C>T synonymous_variant 0.15
inhA 1674876 c.675C>G synonymous_variant 0.13
rpsA 1833489 c.-53T>A upstream_gene_variant 0.29
rpsA 1833495 c.-47_-46insAATC upstream_gene_variant 0.22
rpsA 1833500 c.-41delC upstream_gene_variant 0.22
rpsA 1833541 c.-1T>C upstream_gene_variant 0.29
rpsA 1833554 p.Thr5Gly missense_variant 0.29
rpsA 1833568 c.27G>C synonymous_variant 0.22
rpsA 1833589 c.48A>T synonymous_variant 0.22
rpsA 1833595 c.54T>C synonymous_variant 0.2
rpsA 1833619 c.78A>C synonymous_variant 0.2
rpsA 1833940 c.399C>G synonymous_variant 0.14
rpsA 1833970 c.429G>C synonymous_variant 0.16
rpsA 1833979 c.438T>C synonymous_variant 0.17
rpsA 1834000 c.459G>C synonymous_variant 0.17
rpsA 1834015 c.474G>C synonymous_variant 0.13
rpsA 1834073 p.Lys178* stop_gained 0.94
rpsA 1834249 c.708T>C synonymous_variant 0.18
rpsA 1834435 c.894G>C synonymous_variant 0.17
rpsA 1834451 c.910T>C synonymous_variant 0.17
rpsA 1834465 c.924T>C synonymous_variant 0.2
rpsA 1834468 c.927A>G synonymous_variant 0.21
rpsA 1834474 c.933C>G synonymous_variant 0.21
rpsA 1834489 c.948T>C synonymous_variant 0.21
rpsA 1834498 c.957C>T synonymous_variant 0.21
rpsA 1834528 c.987T>C synonymous_variant 0.2
rpsA 1834546 c.1005T>C synonymous_variant 0.18
rpsA 1834555 c.1014T>C synonymous_variant 0.19
rpsA 1834558 c.1017C>G synonymous_variant 0.2
rpsA 1834606 c.1065C>G synonymous_variant 0.2
rpsA 1834609 c.1068T>C synonymous_variant 0.2
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.2
rpsA 1834633 c.1092A>G synonymous_variant 0.22
rpsA 1834639 c.1098T>C synonymous_variant 0.21
rpsA 1834666 c.1125G>C synonymous_variant 0.22
rpsA 1834669 c.1128G>C synonymous_variant 0.22
rpsA 1834688 c.1147_1149delAGTinsTCC synonymous_variant 0.22
tlyA 1917908 c.-32C>G upstream_gene_variant 0.14
tlyA 1917929 c.-11T>C upstream_gene_variant 0.19
tlyA 1917943 p.Ala2Ser missense_variant 0.18
tlyA 1917951 c.12T>C synonymous_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 0.18
tlyA 1917981 c.42G>C synonymous_variant 0.19
tlyA 1917990 c.51G>C synonymous_variant 0.19
tlyA 1917993 c.54A>G synonymous_variant 0.18
tlyA 1917996 c.57A>G synonymous_variant 0.19
tlyA 1917999 c.60T>C synonymous_variant 0.19
tlyA 1918002 c.63A>G synonymous_variant 0.19
tlyA 1918036 p.Arg33Ser missense_variant 0.13
ndh 2101906 c.1137G>C synonymous_variant 0.17
ndh 2101915 c.1128T>C synonymous_variant 0.18
ndh 2101918 c.1123_1125delAGGinsCGC synonymous_variant 0.17
ndh 2101924 c.1119T>G synonymous_variant 0.17
ndh 2101939 c.1104A>C synonymous_variant 0.22
ndh 2101960 c.1083A>G synonymous_variant 0.21
ndh 2101966 c.1077T>G synonymous_variant 0.21
ndh 2101972 c.1071G>C synonymous_variant 0.21
ndh 2101978 p.Asn355Asp missense_variant 0.21
ndh 2101988 p.Ala352Gly missense_variant 0.21
ndh 2102009 p.Ser345Asn missense_variant 0.21
ndh 2102020 c.1023A>G synonymous_variant 0.21
ndh 2102023 c.1020G>C synonymous_variant 0.21
ndh 2102026 c.1017G>C synonymous_variant 0.21
katG 2155581 c.531C>A synonymous_variant 0.14
katG 2155590 c.522A>G synonymous_variant 0.14
katG 2155616 p.Val166Ile missense_variant 0.12
katG 2155637 p.Leu159Ile missense_variant 0.17
katG 2155641 p.Lys157Asn missense_variant 0.15
katG 2155677 c.435C>G synonymous_variant 0.14
katG 2155680 c.432G>C synonymous_variant 0.14
katG 2155691 c.421T>C synonymous_variant 0.14
katG 2155695 p.Ala139Val missense_variant 0.15
katG 2155701 c.411C>T synonymous_variant 0.17
katG 2155704 c.408C>G synonymous_variant 0.15
katG 2155716 c.396T>C synonymous_variant 0.13
PPE35 2167669 p.Phe982Leu missense_variant 1.0
kasA 2519077 c.963G>C synonymous_variant 0.12
kasA 2519095 c.981C>G synonymous_variant 0.14
kasA 2519098 c.984C>G synonymous_variant 0.14
kasA 2519104 c.990T>A synonymous_variant 0.14
kasA 2519108 p.Asp332Gln missense_variant 0.14
kasA 2519111 p.Gln333Glu missense_variant 0.14
kasA 2519125 c.1011C>T synonymous_variant 0.13
kasA 2519137 c.1023T>C synonymous_variant 0.15
kasA 2519146 c.1032C>A synonymous_variant 0.17
kasA 2519152 c.1038G>A synonymous_variant 0.13
kasA 2519176 c.1062G>A synonymous_variant 0.13
kasA 2519215 c.1101C>T synonymous_variant 0.12
folC 2747040 p.Ile187Val missense_variant 0.12
folC 2747059 c.540T>C synonymous_variant 0.13
folC 2747086 c.513A>C synonymous_variant 0.17
folC 2747089 c.510G>C synonymous_variant 0.17
Rv2752c 3066234 c.-43G>A upstream_gene_variant 0.94
fbiB 3642276 c.743delC frameshift_variant 1.0
fbiB 3642593 c.1059G>C synonymous_variant 0.18
fbiB 3642602 c.1068A>C synonymous_variant 0.18
fbiB 3642605 c.1071A>G synonymous_variant 0.15
fbiB 3642614 c.1080C>T synonymous_variant 0.18
fbiB 3642620 c.1086T>C synonymous_variant 0.18
fbiB 3642656 c.1122G>C synonymous_variant 0.15
fbiB 3642659 c.1125C>G synonymous_variant 0.14
fbiB 3642662 c.1128C>G synonymous_variant 0.14
fbiB 3642668 c.1134A>C synonymous_variant 0.14
rpoA 3877818 c.690A>G synonymous_variant 0.15
rpoA 3877839 c.669G>C synonymous_variant 0.17
rpoA 3877857 c.651G>A synonymous_variant 0.15
rpoA 3877866 c.642G>C synonymous_variant 0.15
rpoA 3877872 c.636C>T synonymous_variant 0.15
rpoA 3877875 c.633T>G synonymous_variant 0.15
rpoA 3877899 p.Ser203Thr missense_variant 0.15
rpoA 3877905 c.603A>G synonymous_variant 0.15
rpoA 3877908 p.Asn200Ser missense_variant 0.15
rpoA 3878106 c.402G>C synonymous_variant 0.13
rpoA 3878111 p.Lys133Gln missense_variant 0.87
rpoA 3878271 c.237T>C synonymous_variant 0.21
rpoA 3878284 p.Glu75Ala missense_variant 0.19
rpoA 3878292 c.216T>C synonymous_variant 0.18
rpoA 3878298 c.210A>G synonymous_variant 0.18
rpoA 3878304 c.204G>C synonymous_variant 0.19
rpoA 3878313 c.195G>C synonymous_variant 0.2
rpoA 3878322 c.186A>G synonymous_variant 0.19
rpoA 3878331 c.177A>G synonymous_variant 0.19
rpoA 3878334 c.174T>C synonymous_variant 0.19
rpoA 3878337 c.171T>C synonymous_variant 0.19
rpoA 3878346 c.162T>C synonymous_variant 0.19
rpoA 3878364 c.144A>G synonymous_variant 0.15
rpoA 3878367 c.141C>G synonymous_variant 0.15
rpoA 3878370 c.138T>C synonymous_variant 0.16
rpoA 3878376 c.132G>C synonymous_variant 0.15
rpoA 3878385 c.123C>G synonymous_variant 0.16
rpoA 3878391 c.117T>C synonymous_variant 0.18
rpoA 3878396 c.112C>T synonymous_variant 0.17
clpC1 4038812 c.1893T>C synonymous_variant 0.2
clpC1 4038815 c.1890G>T synonymous_variant 0.19
clpC1 4038851 c.1854G>A synonymous_variant 0.29
clpC1 4038878 c.1827A>G synonymous_variant 0.27
clpC1 4038908 c.1797C>G synonymous_variant 0.32
clpC1 4038914 c.1791G>C synonymous_variant 0.35
clpC1 4038923 c.1782A>G synonymous_variant 0.28
clpC1 4038932 c.1773G>C synonymous_variant 0.25
clpC1 4038953 c.1752A>G synonymous_variant 0.31
clpC1 4038956 c.1749T>C synonymous_variant 0.27
clpC1 4038965 c.1740T>C synonymous_variant 0.31
clpC1 4038971 c.1734T>C synonymous_variant 0.31
clpC1 4038974 c.1731T>C synonymous_variant 0.31
clpC1 4038989 c.1716T>C synonymous_variant 0.29
clpC1 4038997 c.1708T>C synonymous_variant 0.29
clpC1 4039022 c.1683A>G synonymous_variant 0.31
clpC1 4039073 c.1632C>G synonymous_variant 0.36
clpC1 4039085 c.1620A>G synonymous_variant 0.25
clpC1 4039090 c.1615C>T synonymous_variant 0.21
clpC1 4039097 c.1608G>C synonymous_variant 0.21
clpC1 4039103 c.1602T>C synonymous_variant 0.15
clpC1 4039106 c.1599G>C synonymous_variant 0.15
clpC1 4039112 c.1593C>G synonymous_variant 0.17
clpC1 4039121 c.1584T>C synonymous_variant 0.23
clpC1 4039124 c.1581C>G synonymous_variant 0.23
clpC1 4039142 c.1563A>G synonymous_variant 0.25
clpC1 4039145 c.1560G>C synonymous_variant 0.25
clpC1 4039169 p.Glu512Asp missense_variant 0.24
clpC1 4039172 c.1533A>G synonymous_variant 0.24
clpC1 4039178 c.1527G>C synonymous_variant 0.24
clpC1 4039183 c.1522T>C synonymous_variant 0.27
clpC1 4039187 c.1518G>C synonymous_variant 0.27
clpC1 4039190 c.1515C>G synonymous_variant 0.27
clpC1 4039208 c.1497C>G synonymous_variant 0.27
clpC1 4039226 c.1479T>C synonymous_variant 0.21
clpC1 4039268 c.1437C>G synonymous_variant 0.2
clpC1 4039274 c.1431G>C synonymous_variant 0.2
clpC1 4039388 c.1317C>A synonymous_variant 0.13
clpC1 4039430 c.1275T>C synonymous_variant 0.14
clpC1 4039442 c.1263A>G synonymous_variant 0.2
clpC1 4039448 c.1257A>G synonymous_variant 0.21
clpC1 4039454 c.1251A>G synonymous_variant 0.15
clpC1 4039463 c.1242C>G synonymous_variant 0.14
clpC1 4039481 c.1224T>G synonymous_variant 0.14
clpC1 4039484 c.1221T>G synonymous_variant 0.14
clpC1 4039517 c.1188C>G synonymous_variant 0.19
clpC1 4039524 p.Phe394Tyr missense_variant 0.22
clpC1 4039526 c.1179G>C synonymous_variant 0.22
clpC1 4039547 c.1158C>G synonymous_variant 0.17
clpC1 4039553 c.1152C>G synonymous_variant 0.17
clpC1 4039562 c.1143C>G synonymous_variant 0.17
clpC1 4039565 c.1140G>C synonymous_variant 0.17
clpC1 4039576 p.Ala377Ser missense_variant 0.21
clpC1 4039577 c.1128T>C synonymous_variant 0.22
clpC1 4039586 c.1119G>C synonymous_variant 0.18
clpC1 4039610 c.1095G>C synonymous_variant 0.2
clpC1 4039616 c.1089G>C synonymous_variant 0.18
clpC1 4039622 c.1083C>G synonymous_variant 0.16
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.16
clpC1 4040093 c.612C>G synonymous_variant 0.16
clpC1 4040105 c.600C>G synonymous_variant 0.15
clpC1 4040147 c.558A>G synonymous_variant 0.21
clpC1 4040153 c.552A>G synonymous_variant 0.28
clpC1 4040162 c.543G>C synonymous_variant 0.28
clpC1 4040165 c.540G>C synonymous_variant 0.28
clpC1 4040168 c.537G>C synonymous_variant 0.26
clpC1 4040171 c.534C>G synonymous_variant 0.26
clpC1 4040201 c.504C>G synonymous_variant 0.29
clpC1 4040207 c.498T>C synonymous_variant 0.31
clpC1 4040213 c.490_492delTCTinsAGC synonymous_variant 0.29
clpC1 4040225 c.480A>C synonymous_variant 0.31
clpC1 4040228 c.477G>C synonymous_variant 0.31
clpC1 4040234 c.471C>G synonymous_variant 0.31
clpC1 4040237 c.468C>T synonymous_variant 0.31
clpC1 4040249 c.456A>G synonymous_variant 0.33
clpC1 4040273 c.432T>C synonymous_variant 0.29
clpC1 4040363 c.342A>C synonymous_variant 0.21
clpC1 4040369 c.336C>G synonymous_variant 0.2
clpC1 4040380 c.325T>C synonymous_variant 0.21
clpC1 4040381 c.324T>C synonymous_variant 0.21
clpC1 4040387 c.318A>G synonymous_variant 0.23
clpC1 4040393 c.312G>C synonymous_variant 0.25
clpC1 4040411 c.294T>C synonymous_variant 0.2
clpC1 4040423 c.282A>G synonymous_variant 0.14
clpC1 4040426 c.279T>C synonymous_variant 0.14
clpC1 4040431 c.274T>C synonymous_variant 0.15
panD 4044090 c.192C>T synonymous_variant 0.14
panD 4044096 c.186C>T synonymous_variant 0.14
panD 4044120 c.162A>G synonymous_variant 0.14
panD 4044123 c.159T>C synonymous_variant 0.14
panD 4044138 c.144T>C synonymous_variant 0.15
panD 4044150 c.132A>G synonymous_variant 0.17
embC 4240543 c.681G>C synonymous_variant 0.18
embC 4240561 c.699C>G synonymous_variant 0.17
embC 4240574 p.Val238Leu missense_variant 0.17
embC 4240578 p.Ala239Val missense_variant 0.17
embC 4240582 c.720C>G synonymous_variant 0.17
embC 4240585 c.723C>G synonymous_variant 0.17
embC 4240591 c.729C>G synonymous_variant 0.18
embC 4240594 c.732C>G synonymous_variant 0.17
embC 4240600 c.738G>C synonymous_variant 0.15
embC 4240632 p.Met257Thr missense_variant 0.14
embC 4240654 c.792C>T synonymous_variant 0.14
embC 4240657 c.795G>C synonymous_variant 0.14
embC 4240671 p.Thr270Ile missense_variant 0.14
embC 4240726 c.864G>C synonymous_variant 0.13
embA 4242703 c.-530C>T upstream_gene_variant 1.0
embA 4244284 p.Pro351Arg missense_variant 0.17
embA 4244298 p.Ser356Ala missense_variant 0.17
embA 4244309 c.1077C>G synonymous_variant 0.17
embA 4244312 c.1080T>G synonymous_variant 0.15
embA 4244315 c.1083G>C synonymous_variant 0.14
embA 4244327 c.1095T>C synonymous_variant 0.13
embA 4244337 p.Leu369Val missense_variant 0.14
embA 4244342 c.1110C>G synonymous_variant 0.14
embA 4244366 c.1134C>G synonymous_variant 0.14
embA 4244372 c.1140T>G synonymous_variant 0.14
embA 4244378 c.1146G>A synonymous_variant 0.14
embA 4244396 c.1164T>C synonymous_variant 0.14
embA 4244412 p.Val394Met missense_variant 0.15
embA 4245137 c.1905T>C synonymous_variant 0.13
embA 4245182 c.1950T>C synonymous_variant 0.15
embA 4245194 c.1962G>C synonymous_variant 0.15
embA 4245198 p.Leu656Ile missense_variant 0.14
embA 4245215 c.1983A>G synonymous_variant 0.14
embA 4245222 p.Tyr664Gln missense_variant 0.14
embA 4245407 c.2175G>C synonymous_variant 0.13
embB 4245807 c.-707_-705delTTAinsCTG upstream_gene_variant 0.15
embA 4245820 p.Ser863Thr missense_variant 0.15
embB 4245830 c.-684G>C upstream_gene_variant 0.14
embB 4248143 c.1630T>C synonymous_variant 0.15
embB 4248157 c.1644A>G synonymous_variant 0.16
embB 4249144 c.2631G>C synonymous_variant 1.0
embB 4249469 p.Leu986Met missense_variant 0.15
embB 4249483 c.2970C>G synonymous_variant 0.23
embB 4249486 c.2973T>G synonymous_variant 0.21
embB 4249487 c.2974T>C synonymous_variant 0.21
embB 4249521 p.Ala1003Val missense_variant 0.14
embB 4249525 c.3012T>C synonymous_variant 0.2
embB 4249528 c.3015C>G synonymous_variant 0.2
embB 4249529 p.Ile1006Val missense_variant 0.2
embB 4249532 p.Ala1007Thr missense_variant 0.2
embB 4249537 c.3024A>G synonymous_variant 0.2
embB 4249543 c.3030G>C synonymous_variant 0.21
embB 4249558 c.3045A>C synonymous_variant 0.18
embB 4249564 c.3051C>T synonymous_variant 0.19
embB 4249568 p.Ser1019Thr missense_variant 0.19
embB 4249573 c.3060T>C synonymous_variant 0.2
embB 4249594 c.3081G>C synonymous_variant 0.18
embB 4249600 c.3087A>G synonymous_variant 0.18