TB-Profiler result

Run: SRR13861529
Summary

Run ID: SRR13861529

Sample name:

Date: 03-04-2023 09:34:02

Number of reads: 91792

Percentage reads mapped: 3.06

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5807 p.Val190Phe missense_variant 1.0
mshA 575293 c.-55T>A upstream_gene_variant 1.0
mshA 575414 p.Gly23Ser missense_variant 1.0
rpoB 761222 c.1416G>C synonymous_variant 0.33
rpoC 765124 c.1755G>C synonymous_variant 1.0
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0
rrs 1472108 n.263C>A non_coding_transcript_exon_variant 1.0
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 1.0
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 1.0
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 1.0
rrs 1472133 n.288G>A non_coding_transcript_exon_variant 1.0
rrs 1472135 n.290C>T non_coding_transcript_exon_variant 1.0
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 1.0
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 1.0
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 0.67
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.67
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.67
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.67
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.67
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.75
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.75
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.75
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.78
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.78
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.78
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.78
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.78
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.7
rrs 1472971 n.1126G>C non_coding_transcript_exon_variant 0.78
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.78
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.78
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.78
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.78
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.78
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.78
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.78
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.78
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.78
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.64
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.5
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 0.5
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.8
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.94
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.96
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.96
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.96
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.96
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.97
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.98
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.98
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.98
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.96
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.96
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.98
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.97
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.97
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.97
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.96
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.96
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.96
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.96
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.95
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.83
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.67
rpsA 1834248 p.His236Leu missense_variant 1.0
katG 2154449 p.Ala555Ser missense_variant 1.0
eis 2715396 c.-65delT upstream_gene_variant 1.0
ribD 2987590 p.Leu251Arg missense_variant 1.0
Rv2752c 3064996 p.Thr399Asn missense_variant 1.0
embA 4243540 p.Ala103Asp missense_variant 1.0
embA 4244146 p.Asp305Ala missense_variant 1.0
embB 4249506 c.2994delG frameshift_variant 1.0