TB-Profiler result

Run: SRR13861595

Summary

Run ID: SRR13861595

Sample name:

Date: 03-04-2023 09:35:42

Number of reads: 91400

Percentage reads mapped: 9.15

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoC 765119 p.Gly584Arg missense_variant 1.0
rpoC 766845 p.Arg1159His missense_variant 1.0
mmpL5 776280 p.Arg734His missense_variant 1.0
fbiC 1305195 c.2265T>G synonymous_variant 1.0
embR 1417526 c.-180delA upstream_gene_variant 1.0
rrl 1473960 n.303T>G non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.81
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.9
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.9
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.9
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.9
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.92
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.92
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.92
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.88
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.88
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.81
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.81
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.81
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.81
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.81
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.81
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.82
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.82
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.81
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.8
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.5
rpsA 1833623 c.82_83insG frameshift_variant 1.0
tlyA 1918515 c.576C>T synonymous_variant 1.0
tlyA 1918620 c.681C>A synonymous_variant 1.0
katG 2154539 p.Gln525Lys missense_variant 0.33
katG 2155055 p.Tyr353Asn missense_variant 1.0
PPE35 2169626 c.987C>T synonymous_variant 1.0
eis 2714776 p.Val186Glu missense_variant 1.0
ahpC 2726084 c.-109C>A upstream_gene_variant 1.0
Rv2752c 3065052 p.Glu380Asp missense_variant 1.0
Rv2752c 3065097 c.1095C>T synonymous_variant 1.0
panD 4044175 p.Ala36Asp missense_variant 1.0
embC 4240583 p.Thr241Ala missense_variant 1.0
whiB6 4338609 c.-88T>G upstream_gene_variant 1.0
gid 4407696 c.507C>T synonymous_variant 1.0