Run ID: SRR14801402
Sample name:
Date: 03-04-2023 11:46:06
Number of reads: 1240494
Percentage reads mapped: 99.65
Strain: lineage4.8
Drug-resistance: RR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.8 | Euro-American (mainly T) | T1;T2;T3;T5 | RD219 | 0.98 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761155 | p.Ser450Leu | missense_variant | 0.11 | rifampicin |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
gyrA | 7787 | c.486G>A | synonymous_variant | 1.0 |
rpoC | 764367 | p.Gly333Ala | missense_variant | 0.14 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.95 |
fabG1 | 1673553 | p.Asp38Glu | missense_variant | 0.22 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
PPE35 | 2168149 | p.Pro822Ser | missense_variant | 1.0 |
PPE35 | 2170065 | p.Ala183Gly | missense_variant | 0.2 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
kasA | 2519071 | p.Asp319Glu | missense_variant | 0.15 |
pepQ | 2860159 | p.Ala87Gly | missense_variant | 0.13 |
Rv2752c | 3064823 | p.Val457Leu | missense_variant | 0.17 |
ald | 3087816 | p.Cys333Gly | missense_variant | 0.22 |
fbiD | 3339734 | p.Ala206Gly | missense_variant | 0.67 |
rpoA | 3878641 | c.-134C>G | upstream_gene_variant | 0.58 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
embB | 4247028 | p.Leu172Arg | missense_variant | 0.25 |
embB | 4248933 | p.Asn807Thr | missense_variant | 0.97 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |
Rv3083 | 3448507 | c.5_*1408del | frameshift_variant&stop_lost&splice_region_variant | 1.0 |