TB-Profiler result

Run: SRR16058493
Summary

Run ID: SRR16058493

Sample name:

Date: 03-04-2023 15:51:50

Number of reads: 573480

Percentage reads mapped: 99.48

Strain: lineage4.6.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.1 Euro-American (Uganda) T2 RD724 1.0
lineage4.6.1.1 Euro-American T2-Uganda RD724 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7539 p.Thr80Ala missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620670 c.780C>T synonymous_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776391 p.Asp697Gly missense_variant 0.17
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305451 p.Gly841Ser missense_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674821 p.Leu207Pro missense_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102540 p.Ala168Gly missense_variant 0.36
katG 2155375 p.Val246Gly missense_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fbiD 3339688 p.Thr191Pro missense_variant 0.3
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612280 c.837C>T synonymous_variant 0.1
Rv3236c 3612997 c.120T>G synonymous_variant 0.4
clpC1 4039072 p.Pro545Ala missense_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethA 4328329 c.-856C>G upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0